281d: Difference between revisions
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[[ | ==CRYSTAL STRUCTURE OF THE A-DNA OCTAMER D(GGCATGCC)== | ||
<StructureSection load='281d' size='340' side='right' caption='[[281d]], [[Resolution|resolution]] 2.38Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[281d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=281D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=281D FirstGlance]. <br> | |||
</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=281d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=281d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=281d RCSB], [http://www.ebi.ac.uk/pdbsum/281d PDBsum]</span></td></tr> | |||
<table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
The crystal structure of the self-complementary DNA octamer d(GGCATGCC) has been determined to a resolution of 2.38 A and R factor of 17.1%. The structure is an A-DNA octamer duplex with Watson-Crick base pairing along its length. This sequence extends the investigation of octamer duplexes of the type d(GGX(4)CC) which assume P6(1) packing within the crystallographic unit cell. The A-DNA duplex is non-linear with a helix axis curvature of 7 degrees and bending towards the DNA minor groove. In view of the biological importance of protein recognition of some A-DNA sequences the minor-groove geometry and helix-axis curvature for this structure is compared with all others of the type d(GGXATXCC). | |||
Structure of the A-DNA octamer d(GGCATGCC).,Nunn CM, Neidle S Acta Crystallogr D Biol Crystallogr. 1997 May 1;53(Pt 3):269-73. PMID:15299929<ref>PMID:15299929</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
== | |||
< | |||
[[Category: Neidle, S.]] | [[Category: Neidle, S.]] | ||
[[Category: Nunn, C M.]] | [[Category: Nunn, C M.]] | ||
Revision as of 09:51, 9 June 2014
CRYSTAL STRUCTURE OF THE A-DNA OCTAMER D(GGCATGCC)CRYSTAL STRUCTURE OF THE A-DNA OCTAMER D(GGCATGCC)
Structural highlights
Publication Abstract from PubMedThe crystal structure of the self-complementary DNA octamer d(GGCATGCC) has been determined to a resolution of 2.38 A and R factor of 17.1%. The structure is an A-DNA octamer duplex with Watson-Crick base pairing along its length. This sequence extends the investigation of octamer duplexes of the type d(GGX(4)CC) which assume P6(1) packing within the crystallographic unit cell. The A-DNA duplex is non-linear with a helix axis curvature of 7 degrees and bending towards the DNA minor groove. In view of the biological importance of protein recognition of some A-DNA sequences the minor-groove geometry and helix-axis curvature for this structure is compared with all others of the type d(GGXATXCC). Structure of the A-DNA octamer d(GGCATGCC).,Nunn CM, Neidle S Acta Crystallogr D Biol Crystallogr. 1997 May 1;53(Pt 3):269-73. PMID:15299929[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. References
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