1avt: Difference between revisions

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[[Image:1avt.gif|left|200px]]<br /><applet load="1avt" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1avt.gif|left|200px]]
caption="1avt, resolution 2.0&Aring;" />
 
'''SUBTILISIN CARLSBERG D-PARA-CHLOROPHENYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX'''<br />
{{Structure
|PDB= 1avt |SIZE=350|CAPTION= <scene name='initialview01'>1avt</scene>, resolution 2.0&Aring;
|SITE= <scene name='pdbsite=ACT:SER+Of+Active+Site+Has+Been+Chemically+Modified+To+Inclu+...'>ACT</scene>, <scene name='pdbsite=M1:Ca+Metal+Binding+Site+1'>M1</scene> and <scene name='pdbsite=M2:Ca+Metal+Binding+Site+2'>M2</scene>
|LIGAND= <scene name='pdbligand=NA:SODIUM ION'>NA</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Subtilisin Subtilisin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.62 3.4.21.62]
|GENE=
}}
 
'''SUBTILISIN CARLSBERG D-PARA-CHLOROPHENYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1AVT is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis] with <scene name='pdbligand=NA:'>NA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Subtilisin Subtilisin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.62 3.4.21.62] Known structural/functional Sites: <scene name='pdbsite=ACT:SER+Of+Active+Site+Has+Been+Chemically+Modified+To+Inclu+...'>ACT</scene>, <scene name='pdbsite=M1:Ca+Metal+Binding+Site+1'>M1</scene> and <scene name='pdbsite=M2:Ca+Metal+Binding+Site+2'>M2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AVT OCA].  
1AVT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AVT OCA].  


==Reference==
==Reference==
Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes., Stoll VS, Eger BT, Hynes RC, Martichonok V, Jones JB, Pai EF, Biochemistry. 1998 Jan 13;37(2):451-62. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9425066 9425066]
Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes., Stoll VS, Eger BT, Hynes RC, Martichonok V, Jones JB, Pai EF, Biochemistry. 1998 Jan 13;37(2):451-62. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9425066 9425066]
[[Category: Bacillus licheniformis]]
[[Category: Bacillus licheniformis]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: Stoll, V S.]]
[[Category: Stoll, V S.]]
[[Category: NA]]
[[Category: NA]]
[[Category: boronic acid inhibitors]]
[[Category: boronic acid inhibitor]]
[[Category: hydrolase]]
[[Category: hydrolase]]
[[Category: serine protease]]
[[Category: serine protease]]


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