4cof: Difference between revisions
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''' | ==Crystal structure of a protein== | ||
<StructureSection load='4cof' size='340' side='right' caption='[[4cof]], [[Resolution|resolution]] 2.97Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4cof]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4COF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4COF FirstGlance]. <br> | |||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br> | |||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cof OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cof RCSB], [http://www.ebi.ac.uk/pdbsum/4cof PDBsum]</span></td></tr> | |||
<table> | |||
== Disease == | |||
[[http://www.uniprot.org/uniprot/GBRB3_HUMAN GBRB3_HUMAN]] Autism;Childhood absence epilepsy. Disease susceptibility is associated with variations affecting the gene represented in this entry. | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/GBRB3_HUMAN GBRB3_HUMAN]] GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Aricescu, A R.]] | |||
[[Category: Miller, P S.]] | |||
[[Category: Transport protein]] | |||
Revision as of 08:10, 4 June 2014
Crystal structure of a proteinCrystal structure of a protein
Structural highlights
Disease[GBRB3_HUMAN] Autism;Childhood absence epilepsy. Disease susceptibility is associated with variations affecting the gene represented in this entry. Function[GBRB3_HUMAN] GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. |
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