1ah0: Difference between revisions

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OCA

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-[[Image:1ah0.gif|left|200px]]<br /><applet load="1ah0" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1ah0.gif|left|200px]]
-caption="1ah0, resolution 2.3&Aring;" />
-'''PIG ALDOSE REDUCTASE COMPLEXED WITH SORBINIL'''<br />
+ {{Structure
+|PDB= 1ah0 |SIZE=350|CAPTION= <scene name='initialview01'>1ah0</scene>, resolution 2.3&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene> and <scene name='pdbligand=SBI:SORBINIL'>SBI</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21]
+|GENE=
+}}
+'''PIG ALDOSE REDUCTASE COMPLEXED WITH SORBINIL'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-AH0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa] with <scene name='pdbligand=ACE:'>ACE</scene>, <scene name='pdbligand=NAP:'>NAP</scene> and <scene name='pdbligand=SBI:'>SBI</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AH0 OCA].
+AH0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AH0 OCA].
 ==Reference==
-A 'specificity' pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil., Urzhumtsev A, Tete-Favier F, Mitschler A, Barbanton J, Barth P, Urzhumtseva L, Biellmann JF, Podjarny A, Moras D, Structure. 1997 May 15;5(5):601-12. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9195881 9195881]
+A 'specificity' pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil., Urzhumtsev A, Tete-Favier F, Mitschler A, Barbanton J, Barth P, Urzhumtseva L, Biellmann JF, Podjarny A, Moras D, Structure. 1997 May 15;5(5):601-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9195881 9195881]
 [[Category: Aldehyde reductase]]
 [[Category: Single protein]]
@@ Line 23: / Line 32: @@
 [[Category: sorbinil inhibitor]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:44:23 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 09:57:23 2008''