3iu2: Difference between revisions

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[[Image:3iu2.png|left|200px]]
==Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD90096==
 
<StructureSection load='3iu2' size='340' side='right' caption='[[3iu2]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
<!--
== Structural highlights ==
The line below this paragraph, containing "STRUCTURE_3iu2", creates the "Structure Box" on the page.
<table><tr><td colspan='2'>[[3iu2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IU2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IU2 FirstGlance]. <br>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=096:(2R)-2-{4-HYDROXY-5-METHOXY-2-[3-(4-METHYLPIPERAZIN-1-YL)PROPYL]PHENYL}-3-PYRIDIN-3-YL-1,3-THIAZOLIDIN-4-ONE'>096</scene>, <scene name='pdbligand=MYA:TETRADECANOYL-COA'>MYA</scene><br>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1rxt|1rxt]], [[3iu1|3iu1]]</td></tr>
or leave the SCENE parameter empty for the default display.
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NMT, NMT1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-->
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycylpeptide_N-tetradecanoyltransferase Glycylpeptide N-tetradecanoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.97 2.3.1.97] </span></td></tr>
{{STRUCTURE_3iu2|  PDB=3iu2  |  SCENE=  }}
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iu2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iu2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3iu2 RCSB], [http://www.ebi.ac.uk/pdbsum/3iu2 PDBsum]</span></td></tr>
 
<table>
===Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD90096===
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
==About this Structure==
  <jmolCheckbox>
[[3iu2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IU2 OCA].  
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iu/3iu2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Glycylpeptide N-tetradecanoyltransferase]]
[[Category: Glycylpeptide N-tetradecanoyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]

Revision as of 12:39, 21 May 2014

Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD90096Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD90096

Structural highlights

3iu2 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Related:1rxt, 3iu1
Gene:NMT, NMT1 (Homo sapiens)
Activity:Glycylpeptide N-tetradecanoyltransferase, with EC number 2.3.1.97
Resources:FirstGlance, OCA, RCSB, PDBsum

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

3iu2, resolution 1.73Å

Drag the structure with the mouse to rotate

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OCA
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