1a7s: Difference between revisions

← Older edit Newer edit →

Revision as of 10:54, 20 March 2008

File:1a7s.gif

, resolution 1.12Å

Ligands:

, and

Coordinates:

save as pdb, mmCIF, xml

ATOMIC RESOLUTION STRUCTURE OF HBP

OverviewOverview

Crystals of human heparin binding protein (HBP) diffract to 1.1 A when flash-frozen at 120 K. The atomic resolution structure has been refined anisotropically using SHELXL96. The final model of HBP consists of 221 amino-acid residues of 225 possible, three glycosylation units, one chloride ion, 15 precipitant ethanol molecules and 323 water molecules. The structure is refined to a final crystallographic R factor of 15.9% and Rfree(5%) of 18.9% using all data. A putative protein kinase C activation site has been identified, involving residues 113-120. The structure is compared to the previously determined 2.3 A resolution structure of HBP.

About this StructureAbout this Structure

1A7S is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Atomic resolution structure of human HBP/CAP37/azurocidin., Karlsen S, Iversen LF, Larsen IK, Flodgaard HJ, Kastrup JS, Acta Crystallogr D Biol Crystallogr. 1998 Jul 1;54(Pt 4):598-609. PMID:9761855

Page seeded by OCA on Thu Mar 20 09:54:08 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:1a7s.gif|left|200px]]<br /><applet load="1a7s" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1a7s.gif|left|200px]]
-caption="1a7s, resolution 1.12&Aring;" />
-'''ATOMIC RESOLUTION STRUCTURE OF HBP'''<br />
+ {{Structure
+|PDB= 1a7s |SIZE=350|CAPTION= <scene name='initialview01'>1a7s</scene>, resolution 1.12&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=EOH:ETHANOL'>EOH</scene>
+|ACTIVITY=
+|GENE=
+}}
+'''ATOMIC RESOLUTION STRUCTURE OF HBP'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-A7S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NAG:'>NAG</scene>, <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=EOH:'>EOH</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A7S OCA].
+A7S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A7S OCA].
 ==Reference==
-Atomic resolution structure of human HBP/CAP37/azurocidin., Karlsen S, Iversen LF, Larsen IK, Flodgaard HJ, Kastrup JS, Acta Crystallogr D Biol Crystallogr. 1998 Jul 1;54(Pt 4):598-609. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9761855 9761855]
+Atomic resolution structure of human HBP/CAP37/azurocidin., Karlsen S, Iversen LF, Larsen IK, Flodgaard HJ, Kastrup JS, Acta Crystallogr D Biol Crystallogr. 1998 Jul 1;54(Pt 4):598-609. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9761855 9761855]
 [[Category: Homo sapiens]]
 [[Category: Single protein]]
@@ Line 25: / Line 34: @@
 [[Category: serine protease homolog]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:41:49 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 09:54:08 2008''