4iy0: Difference between revisions
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''' | ==Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4== | ||
<StructureSection load='4iy0' size='340' side='right' caption='[[4iy0]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4iy0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IY0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IY0 FirstGlance]. <br> | |||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene><br> | |||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4iy2|4iy2]], [[4iy3|4iy3]], [[4iy4|4iy4]]</td></tr> | |||
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CNNM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4iy0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iy0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4iy0 RCSB], [http://www.ebi.ac.uk/pdbsum/4iy0 PDBsum]</span></td></tr> | |||
<table> | |||
== Disease == | |||
[[http://www.uniprot.org/uniprot/CNNM2_HUMAN CNNM2_HUMAN]] Familial primary hypomagnesemia with normocalcuria and normocalcemia. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/CNNM2_HUMAN CNNM2_HUMAN]] Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Human]] | |||
[[Category: Accardi, A.]] | |||
[[Category: Corral-Rodriguez, M A.]] | |||
[[Category: Diercks, T.]] | |||
[[Category: Encinar, J A.]] | |||
[[Category: Ereno-Orbea, J.]] | |||
[[Category: Gomez-Garcia, I.]] | |||
[[Category: Martinez-Cruz, L A.]] | |||
[[Category: Muller, D.]] | |||
[[Category: Oyenarte, I.]] | |||
[[Category: Spiwok, V.]] | |||
[[Category: Stuiver, M.]] | |||
[[Category: Terashima, H.]] | |||
[[Category: Bateman domain]] | |||
[[Category: Cb]] | |||
[[Category: Cytosol]] | |||
[[Category: Magnesium sensor]] | |||
[[Category: Magnesium transporter]] | |||
[[Category: Metal transport]] |