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*[[User:Wayne_Decatur/Haloarcula Large Ribosomal Subunit With Azithromycin|Azithromycin bound to the Large Ribosomal Subunit of Haloarcula marismortui]]<br>
*[[User:Wayne_Decatur/Haloarcula Large Ribosomal Subunit With Azithromycin|Azithromycin bound to the Large Ribosomal Subunit of Haloarcula marismortui]]<br>


==Additional Ribosome Structures==
 
<b>Several other ribosome structures have now been published, and here are just a few of these entries in Proteopedia (with apologies to the authors of those not yet listed):<br></b>
==3D structures of BAG family proteins==
*[[2j00]] and [[2j01]] are the subunits of the 70S ribosome structure from the Ramakrishnan lab; the aminoglycoside antibiotic paromomycin is present as well. [[2j02]] and [[2j02]] form another molecule described in the accompanying report.<br>
 
*[[1gix]] and [[1giy]] are the subunits of the 70S ribosome structure determined by the Noller lab, the first for the 70S at near-atomic resolution; more of the mRNA chain is seen in [[1jgo]].<br>
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
*[[2i2u]] and [[2i2v]] are the subunits of the <em>E. coli</em> ribosome at 3.2 &Aring; as solved by the Cate lab. [[2i2t]] and [[2i2p]] are related structures.<br>
 
*[[2gya]] and [[2gy9]] are the subunits of a complete <em>E. coli</em> ribosome as determined by cryo-EM by Joachim Frank's lab.<br>
===30S subunit + RNA===
*[[3u5b]], [[3u5c]], [[3u5d]], [[3u5e]], [[3u5f]], [[3u5g]], [[3u5h]], and [[3u5i]] are the subunits of the eukaryotic 80S ribosome of the baker's yeast ''Saccharomyces cerevisiae'' at a glorious 3.0 &Aring; — including nearly all ribosomal RNA bases and protein side chains.<br>
 
*[[1ibk]] is paromomycin bound to the small subunit.<br>
[[2zm6]], [[1n36]], [[1j5e]], [[3oto]] - Tt30S ribosomal subunit+THX+16S RRNA – Thermus thermophiles<br />
*[[1ibm]] is the small subunit with an mRNA analog bound and an anticodon stem loop bound to the A site.<br>
[[2vqe]], [[2vqf]], [[2uuc]], 2e5l]], [[2uu9]], [[2uua]], [[2uub]], [[3pyn]], [[3pyq]], [[3pys]], [[3pyu]] - Tt30S ribosomal subunit+16S RRNA+RNA fragment<br />
*Small subunit bound to near-cognate tRNA anticodon stem-loop: [[1n32]], [[1n33]], [[1n34]], [[1n36]]<br>
[[3kc4]] - Ec30S ribosomal subunit - Escherichia coli<br />
*[[2ow8]] and [[1vsa]] are the subunits of a 70S-tRNA-mRNA complex from the Noller lab.<br>
[[3i1m]], [[3i1o]], [[3df1]], [[3df3]], [[2vho]], [[2vhp]], [[2avy]], [[2aw7]], [[1pnx]] - Ec30S ribosomal subunit+16S RRNA<br />
*Macrolide, lincosamide, streptogramin B, and ketolide antibiotics bound to the large subunit, which impacts mechanisms of drug resistance:[[1yi2]], [[1yj2]], [[1yit]], [[1yhq]], [[1yjn]], [[1yij]], and [[1yj9]] <br>
[[1i94]], [[1fka]], [[3uxs]], [[3uxt]], [[4dr1]] -  Tt30S ribosomal subunit+16S RRNA<br />
*Refined ''H. marismortui'' 50S ribosomal subunit and its interaction with anisomycin and mutations outside the binding site that make it drug-resistant: [[3cc2]], [[3cc4]], [[3cc7]], [[3cce]], [[3ccj]], [[3ccl]], [[3ccm]], [[3ccq]], [[3ccr]]   [[3ccs]], [[3ccu]], [[3ccv]] and [[3cd6]]   
[[4duy]], [[4duz]], [[4dv0]], [[4dv1]], [[4dv2]], [[4dv3]], [[4dv4]], [[4dv5]], [[4dv6]], [[4dv7]] - Tt30S ribosomal subunit+16S RRNA (mutant)<br />
*Chloramphenicol bound to the ''H. marismortui'' 50S ribosomal subunit: [[1nji]]<br>
[[4dr4]], [[4b3m]], [[4b3r]], [[4b3s]], [[4b3t]] - Tt30S ribosomal subunit+16S RRNA + mRNA<br />
*Chloramphenicol bound to the ''D. radiodurans'' 50S ribosomal subunit: [[1k01]]<br>
[[1p87]] - Ec30S ribosomal subunit+16S RRNA – Cryo-EM<br />
*The antibiotic linezolid (example of the first new class of antibiotics to enter into clinical usage within the past 30 years) bound to the large ribosomal subunit of ''D. radiodurans'': [[3dll]]<br>
[[3bbn]] - s30S ribosomal subunit+16S RRNA – Cryo-EM – spinach<br />
*Thiopeptide antibiotics bound to the large ribosomal subunit of ''D. radiodurans'': [[2zjp]], [[2zjq]],and [[3cf5]]<br>
 
*Macrolide antibiotics bound to the large ribosomal subunit of ''D. radiodurans'': [[2o43]], [[2o44]], and [[2o45]]<br>
=== 30S subunit + chain release factor===
*Ribosome Binding Domain of the Trigger Factor in complex with the large ribosomal subunit of ''D. radiodurans'': [[2d3o]] and [[2aar]]<br>
 
*Initiation factor 1 bound to the small subunit: [[1hr0]]<br>
[[3mr8]], [[3ms0]] – Tt30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+mRNA+16S RRNA <br />
* [[4abr]] and [[4abs]] show the ''Thermus thermophilus'' 50S ribosomal subunit bound by a tmRNA fragment, SmpB and elongation factor Tu at 3.2 &Aring; as solved by the lab of V. Ramakrishnan.
[[3d5a]] [[3d5c]] - Tt30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+E-site tRNA+mRNA +16S RRNA<br />
*70S interaction with the Shine-Dalgarno sequence: [[2qnh]] and [[1vsp]].<br>
[[3zvo]] - Tt30S ribosomal subunit+THX+P-site tRNA Met +mRNA +16S RRNA+chain release factor 3<br />
*Ribosome Recycling Factor bound to the 70S Ribosome: [[2v46]], [[2v47]], [[2v48]], and [[2v49]] <br>
[[2b64]] - Tt30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 1<br />
*[[2e5l]] shows the small subunit with an mRNA mimic bound and the Shine-Dalgarno and anti-Shine-Dalgarno sequences interacting.<br>
[[2b9m]] - Tt30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 2<br />
*70S ribosome in complex with release factors RF1 and RF2 bound to a cognate stop codon: [[2b64]] and [[2b66]]<br>
[[2x9r]], [[2x9t]], [[2wh1]], [[2wh3]] - Tt30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+mRNA +16S RRNA<br />
*Structures of the 30S bound with anticodon stem-loops from tRNAs that facilitate frame-shifting: [[2uxb]], [[2uxc]], and [[2uxd]]<br>
[[3f1e]], [[3f1g]] - Tt30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+E-site tRNA +16S RRNA<br />
*70S Ribosome in complex with mRNA, paromomycin, acylated A- And P-Site tRNAs, and E-Site tRNA: [[2wdg]], [[2wdh]], [[2wdi]], [[2wdj]], [[2wdk]], [[2wdl]], [[2wdm]], and [[2wdn]]<br>
[[4kfh]], [[4kfk]] - Tt30S ribosomal subunit+16S RRNA+ RF-2  + mRNA+ P-site tRNA fMet<br />
* ''E. coli'' 70S ribosome in complex with paramomycin and ribosome recycling factor: [[2qal]], [[2qam]], [[2qan]], [[2qao]], [[2qb9]], [[2qba]], [[2qbb]], [[2qbc]], [[2qbd]], [[2qbe]], [[2qbf]], [[2qbg]], [[2qbh]], [[2qbi]], [[2qbj]], [[2qbk]], [[2z4k]], [[2z4l]], [[2z4m]], and [[2z4n]].<br>
 
*''E. coli'' 70S ribosome intermediates in a key conformational change: [[3i1m]], [[3i1n]], [[3i1o]], [[3i1p]], [[3i1q]], [[3i1r]],[[3i1s]],[[3i1t]],[[3i1z]], [[3i20]], [[3i21]], and [[3i22]].<br>
===30S subunit +tRNA+mRNA===
*''E. coli'' ribosome in complex with the atypical aminoglycoside antibiotic hygromycin B: [[3df1]], [[3df2]],[[3df3]], and [[3df4]].<br>
 
*Structural basis of a mechanism of hydrolytic release of the newly formed polypeptide by the large subunit that may be analogous to that used by release factors:[[3cma]] and [[3cme]]
[[2hgi]] - Tt30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet<br />
*Elongation factor P bound to the 70S ribosome: [[3huw]], [[3hux]], [[3huy]], and [[3huz]].<br>
[[4l6k]], [[4l6m]] - Tt30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA<br />
*''Thermus thermophilus'' 70S ribosome in complex with the cytotoxic domain of colicin E3 (E3-rRNase): [2xfz],[2xg0],[2xg1], and [2xg2]</br>
[[2hgp]] - Tt30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA<br />
*70S ribosome in complex with Ef-Tu and and aminoacyl-tRNA (P- and E- site tRNAs are also present): [[2wrn]], [[2wro]], [[2wrq]], and [[2wrr]]<br>
[[3t1h]], [[3t1y]] - Tt30S ribosomal subunit+16S RRNA+tRNA Lys +mRNA<br />
*70S ribosome in complex with EF-G (P- and E- site tRNAs are also present): [[2wri]] , [[2wrj]], [[2wrk]], and [[2wrl]]<br>
[[3tvf]], [[3tvg]], [[3uyd]], [[3uyf]] - Tt30S ribosomal subunit+16S RRNA+tRNA Leu + tRNA fMet + mRNA<br />
*Structure of stalled ribosome rescuing factor, Yaej, bound to the ''Thermus thermophilus'' 70S Ribosome: [[4dh9]], [[4dha]], [[4dhb]], and [[4dhc]]<br>
[[3zn7]], [[3znd]] - Tt30S ribosomal subunit+16S RRNA+A-site tRNA Ile agmatidine + E-site tRNA Ile agmatidine + mRNA<br />
* EF-G–Ribosome Complexes (''Thermus thermophilus'') Trapped in Intermediate States of Translocation with β,γ-imidoguanosine 5′-triphosphate (GDPNP) or fusidic acid: [[4kcy|4kcy with GDPNP-I]], [[4kcz|4kcz with GDPNP-I]], [[4kd0|4kd0 with GDPNP-I]], [[4kd2|4kd2 with GDPNP-I]], [[4kbt|4kbt with GDPNP-2]], [[4kbu|4kbu with GDPNP-2]], [[4kbv|4kbv with GDPNP-2]], [[4kbw|4kbw with GDPNP-2]], [[4kd8|4kd8 with Fus-3.6]], [[4kd9|4kd9 with Fus-3.6]], [[4kda|4kda with Fus-3.6]], [[4kdb|4kdb with Fus-3.6]], [[4kdg|4kdg with Fus-4.2]], [[4kdh|4kdh with Fus-4.2]], [[4kdj|4kdj with Fus-4.2]], [[4kdk|4kdk with Fus-4.2]]<br>
[[3uz6]], [[3uz7]], [[3uzg]], [[3uzi]] - Tt30S ribosomal subunit+16S RRNA+tRNA Tyr + tRNA fMet + mRNA<br />
*Elongation Factor G Bound to the ''Thermus thermophilus'' Ribosome in an Intermediate State of Translocation :[[4juw]] and [[4jux]]<br>
[[2i2p]], [[2i2u]] - Ec30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA<br />
*Control of Ribosomal Subunit Rotation by Elongation Factor G (''Escherichia coli''): [[4kix]], [[4kiy]], [[4kiz]], [[4kj0]], [[4kj1]], [[4kj2]], [[4kj3]], [[4kj4]], [[4kj5]], [[4kj6]], [[4kj7]], [[4kj8]], [[4kj9]], [[4kja]], [[4kjb]], and [[4kjc]]<br>
[[2hgr]], [[3v6u]], [[3v6v]], [[4ej9]], [[4eja]] - Tt30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet+mRNA<br />
*[[3o2z]], [[3o30]], [[3o58]], and [[3o5h]] are the subunits of the eukaryotic 80S ribosome of the baker's yeast ''Saccharomyces cerevisiae''.<br>
[[1yl4]] – Tt30S ribosomal subunit+ tRNA Phe+16S RRNA+THRS mRNA operator<br />
*The eukaryotic (''S. cerevisiae'') ribosome at atomic resolution using cryo-EM reconstruction and protein [[Theoretical models#Homology Models|homology modeling]]: [[3jyx]], [[3jyw]], and [[3jyv]] <br>
[[1pns]] - Ec30S ribosomal subunit+ tRNA Phe+16S RRNA+mRNA <br />
*The bacterial ''B. subtilis'' 50S ribosome assembly intermediates at atomic resolution using cryo-EM reconstruction:[[3j3v]] and [[3j3w]]
[[3j13]] - Ec30S ribosomal subunit+ P-site tRNA +16S RRNA+mRNA – Cryo-EM<br />
*''Drosophila melanogaster'' 80S ribosome in complex with the translation factor eEF2, E-site transfer RNA and Stm1-like proteins, based on high-resolution cryo-electron-microscopy density maps: [[3j38]], [[3j39]], [[3j3c]], [[3j3e]]
[[3j0u]], [[3j0v]], [[3j0x]], [[3j0z]], [[3j10]], [[3j20]] - Ec30S ribosomal subunit+ A-site tRNA + P-site tRNA +16S RRNA+mRNA – Cryo-EM<br />
*Human 80S ribosome in complex with the translation factor eEF2, E-site transfer RNA and Stm1-like proteins, based on high-resolution cryo-electron-microscopy density maps: [[3j3a]], [[3j3b]], [[3j3d]], [[3j3f]]
[[1xnq]], [[1xnr]] - Tt30S ribosomal subunit+THX+mRNA+tRNA anticodon+16S RRNA<br />
*High-resolution cryo-electron microscopy structure of the ''Trypanosoma brucei'' ribosome: [[3zeq]], [[3zex]],[[3zey]], [[3zf7]]
[[4gkj]], [[4gkk]] - Tt30S ribosomal subunit +16S RRNA +THX + mRNA + tRNA Met<br />
*High-resolution cryo-electron microscopy structure of the large subunit of the mammalian mitochondrial ribosome: [[4ce4]]
[[4jv5]], [[4jya]], [[4k0k]], [[4k0l]] - Tt30S ribosomal subunit +16S RRNA +THX + mRNA + ASL-tRNA <br />
*High-resolution cryo-electron microscopy structure of the large subunit of the yeast mitochondrial ribosome: [[3j6b]]
 
===30S subunit +A-site tRNA===
 
[[2uxd]], [[2uxc]] -  Tt30S ribosomal subunit+THX+A-site mRNA CGGG+tRNA anticodon+16S RRNA<br />
[[1n32]], [[1n33]] - Tt30S ribosomal subunit+THX+A-site mRNA fragment+tRNA anticodon+16S RRNA<br />
[[1n34]] - Tt30S ribosomal subunit+THX+A-site mRNA fragment +16S RRNA<br />
1xmo]], 1xmq]] - Tt30S ribosomal subunit+THX+A-site mRNA+tRNA anticodon+16S RRNA<br />
[[2uxb]] - Tt30S ribosomal subunit+THX+A-site mRNA GGGU+tRNA anticodon+16S RRNA<br />
 
===30S subunit+P-site tRNA===
 
[[3i8g]] - Tt30S ribosomal subunit+P-site tRNA+mRNA +16S RRNA<br />
[[3i8h]], [[3i9b]], [[3i9d]] - Tt30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA<br />
[[1ibk]] - Tt30S ribosomal subunit+THX+P-site mRNA fragment +16S RRNA<br />
[[2wwl]] - Ec30S ribosomal subunit+Poly-Ala chain+P-site tRNA+mRNA +16S RRNA <br />
[[3i1q]] - Ec30S ribosomal subunit+P-site tRNA hairpin+mRNA <br />
[[3i1s]], [[3i1z]], [[3i21]] - Ec30S ribosomal subunit+P-site tRNA hairpin+mRNA +16S RNA<br />
[[2om7]] – TtRPS2+TtRPS12+TtRPL1+ P-site tRNA+16S RRNA fragment+23S RRNA fragment<br />
 
===30S subunit+A-site tRNA+P-site tRNA===
[[1ibl]], [[1ibm]] - Tt30S ribosomal subunit+THX+A-site mRNA fragment+P-site mRNA fragment+tRNA anticodon+16S RRNA<br />
 
===30S subunit+P-site tRNA+E-site tRNA ===
 
[[2ow8]] - Tt30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA+mRNA +16S RRNA<br />
[[2b9o]] - Tt30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA<br />
[[2qnh]] - Tt30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA<br />
[[2wdg]], [[2wdh]], [[2wdk]], [[2wdm]] - Tt30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA+tRNA Phe<br />
 
===30S subunit+A-site tRNA+P-site tRNA+E-site tRNA===
 
[[2gy9]], [[2gyb]] -  Ec30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA – Cryo-EM<br />
[[1jgo]], [[1jgp]], [[1jgq]], [[1gix]] -  Tt30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+tRNA Phe+mRNA +16S RRNA<br />
[[4k0p]] - Tt30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA +mRNA +16S RRNA<br />
[[3e1a]], [[3e1c]] -  Ec30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA<br />
 
===30S subunit + antibiotics===
 
[[1i95]], [[1i97]], [[2hhh]], [[2f4v]], [[3oge]], [[3ogy]], [[3ohc]], [[3ohd]], [[3ohy]], [[3oi0]], [[3oi2]], [[3oi4]], [[4dr3]] -  Tt30S ribosomal subunit+16S RRNA+antibiotic<br />
[[1hnx]], [[1hnw]], [[1hnz]], [[1fjg]], [[4aqy]], [[4dr5]], [[4dr6]], [[4dr7]], [[4khp]] - Tt30S ribosomal subunit+16S RRNA+mRNA fragment+antibiotic <br />
[[2qbb]], [[2qb9]], [[1vs5]], [[1vs7]] , [[2qan]], [[2qal]], [[2qou]], [[2qow]], [[2qoy,]] [[2qp0]], [[2z4k]], [[2z4m]], [[3oaq]], [[3oar]], [[3ofa]], [[3ofb]], [[3ofo]], [[3ofp]], [[3ofx]], [[3ofy]], [[3or9]], [[3ora]] - Ec30S ribosomal subunit+16S RRNA+antibiotic<br />
[[4gaq]], [[4gas]] - Ec30S ribosomal subunit+16S RRNA+ mRNA + antibiotic<br />
[[3sfs]] - Ec30S ribosomal subunit+16S RRNA+ mRNA + RF-3 + antibiotic<br />
[[2j00]], [[2j02]] - Tt30S ribosomal subunit+16S RRNA+paromomycin+P-site tRNA fMet+E-site tRNA Phe+mRNA<br />
[[3knl]], [[3knm]], [[3knn]], [[3kno]], [[3knj]], [[3knh]] - Tt30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+ antibiotic<br />
[[3uz3]], [[3uz4]] - Tt30S ribosomal subunit+16S RRNA+tRNA Leu + tRNA fMet + mRNA + paromomycin<br />
[[4g5k]], [[4g5m]], [[4g5t]], [[4g5v]] - Tt30S ribosomal subunit+16S RRNA + tRNA fMet + mRNA + antibiotics<br />
[[3uzl]], [[3uzm]] - Tt30S ribosomal subunit+16S RRNA+tRNA Tyr + tRNA fMet + mRNA + paromomycin<br />
 
===30S subunit + ribosome recycling factor===
 
[[2qbd]], [[2qbf]] - Ec30S ribosomal subunit+16S RRNA+ribosome recycling factor<br />
[[3r8n]], [[3r8o]], [[4gd1]], [[4gd2]] - Ec30S ribosomal subunit+16S RRNA+ribosome recycling factor + mRNA + tRNA<br />
[[2qbh]], [[2qbj]] - Ec30S ribosomal subunit+16S RRNA+ribosome recycling factor+gentamicin<br />
[[2v46]], [[2v48]] -  Tt30S ribosomal subunit+16S RRNA+ribosome recycling factor+P-site tRNA Phe+mRNA+tRNA fMet<br />
 
===30S subunit + elongation factor===
 
[[2wri]], [[2wrk]] - Tt30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA+elongation factor G<br />
[[2wrn]], [[2wrq]] - Tt30S ribosomal subunit+THX+A-site tRNA+mRNA +16S RRNA+elongation factor TU-4<br />
[[3fic]] - Tt30S ribosomal subunit+THX+A-site tRNA+P-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU-A<br />
[[4abr]] - Tt30S ribosomal subunit+THX + E/P-site tRNA fMet +mRNA codon+16S RRNA+elongation factor TU<br />
[[2y0u]], [[2y0w]], [[2y0y]], [[2y12]], [[2y10]], [[2y18]], [[2y14]], [[2y16]] - Tt30S ribosomal subunit+THX+A-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU<br />
[[3fih]] - Ec30S ribosomal subunit+A-site tRNA Phe+P-site tRNA+mRNA +16S RRNA+elongation factor TU<br />
[[3izv]] - Ec30S ribosomal subunit+A/T-site tRNA Phe +16S RRNA+elongation factor TU<br />
[[3j18]] - Ec30S ribosomal subunit+A/T-site tRNA Phe +16S RRNA+ mRNA + SSRA-binding protein + formyl-Met specific initiator tRNA + elongation factor G – Cryo-EM<br />
[[3izw]] - Ec30S ribosomal subunit+A-site tRNA Phe +mRNA +16S RRNA+elongation factor TU<br />
[[3huw]], [[3huy]] - Tt30S ribosomal subunit+THX+tRNA-Met+mRNA +16S RRNA+elongation factor P<br />
[[4b8f]], [[4b8h]] - Tt30S ribosomal subunit+THX+RNA+mRNA +16S RRNA+elongation factor G<br />
[[4btc]], [[4kdg]], [[4kdj]] - Tt30S ribosomal subunit+THX+RNA +16S RRNA+elongation factor G<br />
[[4juw]] - Tt30S ribosomal subunit+THX+ tRNA Phe +16S RRNA + mRNA +elongation factor G<br />
[[4kbt]], [[4kbv]], [[4kcy]], [[4kd0]], [[4kd8]], [[4kda]] - Tt30S ribosomal subunit+THX+ tRNA Met +16S RRNA + mRNA + viomycin + elongation factor G<br />
[[4kiy]], [[4kj0]], [[4kj2]], [[4kj4]], [[4kj6]], [[4kj8]], [[4kja]], [[4kjc]] - Ec30S ribosomal subunit +16S RRNA + viomycin + elongation factor G<br />
 
===30S subunit + translation initiation factor===
 
[[1hr0]] - Tt30S ribosomal subunit+THX+IF+16S RRNA<br />
[[1i96]] -  Tt30S ribosomal subunit+THX+IF3+16S RRNA<br />
 
===30S subunit + various proteins===
 
[[3kiq]], [[3kis]], [[3kiu]], [[3kix]] - Tt30S ribosomal subunit+toxin RelE+16S RRNA<br />
[[2xfz]], [[2xg1]] - Tt30S ribosomal subunit+colicin-E3 fragment+16S RRNA+mRNA+E-site tRNA+THX<br />
[[1voq]], [[1vos]] , [[1vov]], [[1vox]], [[1voz]] - Ec30S ribosomal subunit+protein Y+16S RRNA<br />
[[3j36]] - Ec30S ribosomal subunit+ tetracycline resistance protein +16S RRNA + mRNA + P-tRNA – Cryo-EM<br />
[[1x18]] – TtRPS2+TtRPS7+TtRPS11+TtRPS18+GTP-binding protein ERA+RNA fragments<br />
[[4dh9]], [[4dhb]] - Tt30S ribosomal subunit +16S RRNA+mRNA+P-site tRNA fMet +THX + YAEJ<br />
[[3v22]], [[3v24]], [[3v26]], [[3v28]] - Tt30S ribosomal subunit +16S RRNA +THX + modulation factor<br />
[[3v2c]], [[3v2e]] - Tt30S ribosomal subunit +16S RRNA +THX + ribosome-associated inhibitor<br />
[[3j00]] – EcRPS2 + 16S RRNA + FTSQ + apolipoprotein A-I<br />
[[2ykr]] - EcRPS2 + 16S RRNA + GMPPNP + GTPase RSGA<br />
[[4a2i]] - EcRPS2 + 16S RRNA + GTPase RSGA – Cryo EM<br />
[[3uoq]] - EcRPS2 + 16S RRNA + mRNA + peptide chain release factor<br />
[[4adv]] - EcRPS2 + 16S RRNA + methyltransferase – Cryo EM<br />
 
===40S ribosomal subunit===
 
[[3jyv]] - Tl40S ribosomal subunit+RACK1+S19E+P-site tRNA – Thermomyces lanuginosus<br />
[[2xzm]], [[2xzn]] - Tet40S ribosomal subunit+RACK1 – Tetrahymena thermophila<br />
[[1s1h]] - y40S ribosomal subunit+18S RRNA+elongation factor 2 – Cryo-EM – yeast<br />
[[3izb]] - y40S ribosomal subunit+ RACK1 – Cryo-EM<br />
[[3o2z]], [[3o30]] - y40S ribosomal subunit+ RACK1<br />
[[3u5c]], [[3u5g]] - y40S ribosomal subunit+ RACK1 + suppressor protein SMT1<br />
[[3iz6]] - w40S ribosomal subunit+RACK1 – wheat<br />
[[3j38]] - Dm40S ribosomal subunit + EF-2 + guanine nucleotide-binding protein – Drosophila melanogaster – Cryo-EM<br />
[[3j3a]] - h40S ribosomal subunit + EF-2 + guanine nucleotide-binding protein – human – Cryo-EM<br />
[[4kzx]] - r40S ribosomal subunit+ RACK1 + EIF1 – rabbit – Cryo-EM<br />
[[4kzy]] - r40S ribosomal subunit+ RACK1 + EIF1 + EIF1A – Cryo-EM<br />
[[4kzz]] - r40S ribosomal subunit+ RACK1 + EIF1A + initiator tRNA – Cryo-EM<br />
[[2zkq]] – d40S ribosomal subunit+RACK1+RRNA fragment – dog - Cryo-EM<br />
[[3zey]] - Tb40S ribosomal subunit – Trypanosoma brucei – Cryo-EM<br />
[[4bpe]], [[4bpn]], [[4bpo]], [[4bpp]] - r40S ribosomal subunit+ 18SRRNA + EIF1 + EIF1A <br />
 
===50S subunit+RNA===
 
[[2x9s]], [[2x9u]], [[3kni]], [[3knk]], [[3knm]], [[3kno]], 3hux]], 3huz]], [[2wdi]], [[2wdj]] [[2wdl]] [[1vsp]], [[2v47]] , [[2v49]], [[1vsa]], [[3pyo]], [[3pyr]], [[3pyt]], [[3pyv]], [[3v6w]], [[3v6x]], [[3zne]], [[4btd]], [[4ejb]], [[4ejc]], [[4k0m]], [[4k0q]], [[2wrj]], [[2wrl]], [[2wro]], [[2wrr]], [[2wh2]], [[2wh4]], [[2hgj]],  [[2hgq]], [[2hgu]],[[2j01]], [[2j03]], [[1yl3]],  [[3i8i]], [[3f1f]], [[3f1h]], [[2b66]], [[2b9n]], [[2b9p]], [[1giy]], [[2xqe]], [[2y0v]], [[2y0x]], [[2y0z]], [[2y11]], [[2y13]], [[2y15]], [[2y17]], [[2y19]], [[3zvp]], [[4abs]], [[4b8g]], [[4b8i]], [[4jux]], [[4kbu]], [[4kbw]], [[4kcz]], [[4kd2]], [[4kd9]], [[4kdb]], [[4kdh]], [[4kdk]], [[4kfi]], [[4kfl]] -  Tt50S subunit+5S RRNA+23S RRNA <br />
[[2xg0]], [[2xg2]], [[3kir]], [[3kit]], [[3kiw]], [[3kiy]] – Tt50S subunit+RNA fragments<br />
[[3fin]], [[2xtg]], [[2xux]] - Tt50S subunit+5S RRNA+23S RRNA – Cryo-EM<br />
[[2wwq]] – Ec 50S subunit+5S RRNA+23S RRNA+mRNA+P-site tRNA <br />
[[3i1n]], [[3i1p]], [[3i1r]], [[3i1t]], [[3i20]], [[3i22]], [[3e1b]], [[3e1d]], [[3df2]], [[3df4]], [[2vhn]], [[2qov]], [[2qox]], [[2i2t]], [[2i2v]], [[1vs6]], [[1vs8]], [[2aw4]], [[2awb]], [[3ofd]], [[3og0]], [[3oas]], [[3oat]], [[3uos]], [[3r8s]], [[3r8t]], [[3j37]], [[4kix]], [[4kiz]], [[4kj1]], [[4kj3]], [[4kj5]], [[4kj7]], [[4kj9]], [[4kjb]] - Ec50S subunit+5S RRNA+23S RRNA <br />
[[3fik]], [[2gya]], [[2gyc]], [[1p85]], [[1p86]], [[3izt]], [[3izu]], [[3j0t]], [[3j0w]], [[3j0y]], [[3j11]], [[3j12]], [[3j14]], [[3j19]] -  Ec50S subunit+5S RRNA+23S RRNA – Cryo-EM<br />
[[3kcr]] - Ec50S subunit+5S RRNA+23S RRNA+preprotein translocase<br />
[[3bbo]] -  s50S subunit+5S RRNA+23S RRNA+4.8S RRNA – Cryo-EM <br />
[[2zjq]], [[2zjr]], [[1nkw]] - Dr50S subunit+5S RRNA+23S RRNA – Deinococcus radiodurans<br />
[[2qa4]], [[3cc2]], [[1s72]], [[4hub]], [[1kqs, 1qvg, [[1jj2, [[1ffk  -  Hm50S subunit+5S RRNA+23S RRNA – Haloarcula marismortui<br />
[[3cc7]], [[3cce]], [[3ccj]], [[3ccl]], [[3ccm]], [[3ccq]], [[3ccr]], [[3ccs]], [[3ccu]], [[3ccv]] -  Hm50S subunit+5S RRNA+23S RRNA (mutant) <br />
[[1yj9]] - Hm50S subunit (mutant)+5S RRNA+23S RRNA <br />
[[1qvf]]- Hm50S subunit+5S RRNA+23S RRNA + deacylated tRNA minihelix<br />
[[1q86]] - Hm50S subunit+5S RRNA+23S RRNA+CCA-Phe-caproic acid-biotin<br />
[[3cma]], [[3cme]], [[1vq8]], [[1vq9]], [[1m90]] - Hm50S subunit+5S RRNA+23S RRNA+CCA+CCA-Phe-CAP-BIO<br />
[[1vq4]], [[1vq5]], [[1vq7]], [[1vql]], [[1vqm]], [[1vqp]] – Hm50S subunit+5S RRNA+23S RRNA+transition state analog<br />
[[1vq6]], [[1vqk]], [[1vqn]] – Hm50S subunit+5S RRNA+23S RRNA+ c-hpmn+CCA-Phe-caproic acid-biotin<br />
[[1vqo]] – Hm50S subunit+5S RRNA+23S RRNA+ CCPMN<br />
[[3iy9]] – 50S subunit – Leishmania taretolae<br />
[[2ftc]] – 50S subunit+5S RRNA+23S RRNA – bovine - Cryo_EM<br />
[[3j21]] –  50S subunit + P0 + LX – Pyrococcus furiosus – Cryo EM<br />
[[3j3v]], [[3j3w]] - 50S subunit+5S RRNA+23S RRNA – Bacillus subtilis<br />
 
=== 50S subunit + antibiotics===
 
[[3dll]], [[2zjp]], [[3cf5]], [[1xbp]], [[1sm1]], [[1nwx]], [[1nwy]], [[3pio]], [[3pip]] - Dr50S subunit+5S RRNA+23S RRNA+general stress protein Ctc+ antibiotic<br />
[[4io9]], [[4ioa]], [[4ioc]] - Dr50S subunit+5S RRNA+23S RRNA+ antibiotics<br />
[[2qba]], [[2qbc]], [[4gar]], [[4gau]], [[2qam, [[2qao, [[2qoz, [[2qp1]], [[3ofc]], [[3ofz]], [[3ofq]], [[3ofr]], [[1vt2]], [[3orb]], [[4l6j]], [[4l6l]]  - Ec50S subunit+5S RRNA+23S RRNA+ antibiotics<br />
[[3i55,]] [[3i56]] , [[3g4s]], [[3g4e]], [[3g71]], [[2qex]], [[3cc4]], [[3cd6]], [[1yhq]], [[1yi2]], [[1yij]], [[1yjn]], [[1yjw]], [[2otj]], [[2otl]], [[1yit]], [[1k73]], [[1kc8]], [[1k8a]], [[1k9m]], [[1kd1]], [[1m1k]], [[3cpw]], [[1yit]], [[1q7y]], [[1q81]], [[1q82]], [[1n8r]], [[1nji]], [[3cxc]] - Hm50S subunit+5S RRNA+23S RRNA + antibiotics<br />
[[3oh5]], [[3oh7]], [[3ohj]], [[3ohk]], [[3ohz]], [[3oi1]], [[3oi3]], [[3oi5]] - Tt50S subunit+5S RRNA+23S RRNA+antibiotic <br />
 
=== 60S subunit===
 
[[3jyw]] -  60S subunit – Thermomyces lanuginosus – Cryo-EM<br />
[[1s1i]], [[1s1h]] - y60S ribosomal subunit+ 5.8S RRNA+ 5S RRNA – Cryo-EM <br />
[[3izs]] - y60S subunit – Cryo-EM<br />
[[3u5e]], [[3u5i]] - y60S subunit <br />
[[3o58]], [[3o5h]] - y60S ribosomal subunit+ 5.8S RRNA+ 5S RRNA + 25S RRNA<br />
[[3izr]], [[3izt]], [[3izu]], [[3izs]] - w60S subunit <br />
[[3j39]] – Dm60S subunit – Cryo-EM<br />
[[3j3b]] – h60S subunit – Cryo-EM<br />
[[4a17]], [[4a1a]], [[4a1c]], [[4a1e]] - Tet60S ribosomal subunit + 5S RRNA + 5.8S RRNA <br />
[[3zf7]] - Tb60S subunit - Cryo EM<br />
 
=== large + small ribosomal subunit===
 
[[1ml5]] - Ec50S ribosomal subunit+30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+tRNA Phe+mRNA fragment+23S RRNA+5S RRNA+16S RRNA – Cryo-EM<br />
[[2zkr]] -  d60S ribosomal subunit+30S ribosomal subunit+28S RRNA+5.8S RRNA – Cryo-EM <br />
[[3j0l]] - r60S ribosomal subunit+40S ribosomal subunit+RRNA fragments+ mRNA fragments – Cryo-EM <br />
[[3j0o]], [[3j0p]], [[3j0q]] - r60S ribosomal subunit+40S ribosomal subunit+RRNA fragments+ mRNA fragments + tRNA – Cryo-EM<br />
 
=== 50S subunit + ribosome releasing factor (RRF)===
 
[[2qbe]], [[2qbg]], [[2qbi]], [[2qbk]], [[2z4l]], [[2z4n]] - Ec50S subunit+5S RRNA+23S RRNA+RRF<br />
[[2rdo]] - Ec50S subunit+5S RRNA+23S RRNA+EF-G+RRF – Cryo-EM<br />
[[3j0d]] - Tt50S subunit+5S RRNA+23S RRNA+RRF – Cryo-EM<br />
 
=== 50S subunit + various proteins===
 
[[2vhm]] - Ec50S subunit+5S RRNA+23S RRNA+PDF C-terminal helix<br />
[[2j28]] - Ec50S subunit+5S RRNA+23S RRNA+signal recognition particle – Cryo-EM<br />
[[1vor]], [[1vou]], [[1vow]], [[1voy]], [[1vp0]], [[1pnu]], [[1pny]] - Ec50S subunit+5S RRNA+23S RRNA+general stress protein Ctc<br />
[[3j01]] - Ec 50S subunit+5S RRNA+23S RRNA + SECYE – Cryo-EM<br />
[[w2b]] - Hm50S subunit+5S RRNA+23S RRNA+trigger factor N-terminal<br />
 
===60S subunit + various proteins===
 
[[4a18]], [[4a19]], [[4a1b]], [[4a1d]] - Tet60S subunit+ 26S RRNA+ translation initiation factor 6 <br />
[[3izs]] – y60S subunit + P0 + P1 + P2 - Cryo EM<br />
[[3u5i]] – y60S subunit + P0<br />
[[4b6a]] – y60S subunit + P0 + P1 + P2 + ARX1 - Cryo EM<br />
[[3o5h]] – y60S subunit + 5S RRNA + 5.8S RRNA + 25S RRNA + P0<br />
[[3j39]] – Dm60S subunit + P0 – Drosophila melanogaster - Cryo EM<br />
[[3j3b]] – h60S subunit + P0 + P1 + P2 – human - Cryo EM<br />
 


==See Also==
==See Also==

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Wayne Decatur, Eric Martz, Eran Hodis, Jaime Prilusky, David Canner, Alexander Berchansky, Michal Harel, Joel L. Sussman, Margaret Franzen
Retrieved from "https://proteopedia.openfox.io/w/Ribosome"