4pxu: Difference between revisions
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{{STRUCTURE_4pxu| PDB=4pxu | SCENE= }} | |||
===Structural basis for the assembly of the mitotic motor kinesin-5 into bipolar tetramers=== | |||
{{ABSTRACT_PUBMED_24714498}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/KL61_DROME KL61_DROME]] Important role in mitotic dividing cells. Microtubule motor required for spindle body separation. Slow plus-end directed microtubule motor capable of cross-linking and sliding apart antiparallel microtubules, thereby pushing apart the associated spindle poles during spindle assembly and function. | |||
==About this Structure== | |||
[[4pxu]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PXU OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024714498</ref><references group="xtra"/><references/> | |||
[[Category: Al-Bassam, J.]] | |||
[[Category: Nithianantham, S.]] | |||
[[Category: Scholey, J E.]] | |||
[[Category: Scholey, J M.]] | |||
[[Category: Anti-parallel four-helix bundle]] | |||
[[Category: Bipolar assembly domain of kinesin-5]] | |||
[[Category: Bipolar tetramer]] | |||
[[Category: Cell cycle]] | |||
[[Category: Coiled-coil]] | |||
[[Category: Crosslinking adjacent microtubules into bundles throughout the mitotic spindle]] | |||
[[Category: Kinesin-5 functions via a sliding filament mechanism]] | |||
[[Category: Microtubule]] |