1ryw: Difference between revisions

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[[Image:1ryw.png|left|200px]]
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===C115S MurA liganded with reaction products===
===C115S MurA liganded with reaction products===
{{ABSTRACT_PUBMED_15531591}}


 
==Function==
<!--
[[http://www.uniprot.org/uniprot/MURA_ENTCL MURA_ENTCL]] Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine. Target for the antibiotic phosphomycin.
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{{ABSTRACT_PUBMED_15531591}}


==About this Structure==
==About this Structure==
[[1ryw]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacter_cloacae Enterobacter cloacae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RYW OCA].  
[[1ryw]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacter_cloacae Enterobacter cloacae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RYW OCA].  
==See Also==
*[[Enoylpyruvate transferase|Enoylpyruvate transferase]]


==Reference==
==Reference==
<ref group="xtra">PMID:015531591</ref><references group="xtra"/>
<ref group="xtra">PMID:015531591</ref><references group="xtra"/><references/>
[[Category: Enterobacter cloacae]]
[[Category: Enterobacter cloacae]]
[[Category: UDP-N-acetylglucosamine 1-carboxyvinyltransferase]]
[[Category: UDP-N-acetylglucosamine 1-carboxyvinyltransferase]]

Revision as of 13:59, 16 April 2014

Template:STRUCTURE 1ryw

C115S MurA liganded with reaction productsC115S MurA liganded with reaction products

Template:ABSTRACT PUBMED 15531591

FunctionFunction

[MURA_ENTCL] Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine. Target for the antibiotic phosphomycin.

About this StructureAbout this Structure

1ryw is a 8 chain structure with sequence from Enterobacter cloacae. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Eschenburg S, Priestman M, Schonbrunn E. Evidence that the fosfomycin target Cys115 in UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) is essential for product release. J Biol Chem. 2005 Feb 4;280(5):3757-63. Epub 2004 Nov 5. PMID:15531591 doi:10.1074/jbc.M411325200

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