1j87: Difference between revisions
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{{STRUCTURE_1j87| PDB=1j87 | SCENE= }} | {{STRUCTURE_1j87| PDB=1j87 | SCENE= }} | ||
===HUMAN HIGH AFFINITY FC RECEPTOR FC(EPSILON)RI(ALPHA), HEXAGONAL CRYSTAL FORM 1=== | ===HUMAN HIGH AFFINITY FC RECEPTOR FC(EPSILON)RI(ALPHA), HEXAGONAL CRYSTAL FORM 1=== | ||
{{ABSTRACT_PUBMED_11531339}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/FCERA_HUMAN FCERA_HUMAN]] Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines. | |||
==About this Structure== | ==About this Structure== | ||
[[1j87]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J87 OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:011531339</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Garman, S C.]] | [[Category: Garman, S C.]] | ||
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[[Category: Ige receptor]] | [[Category: Ige receptor]] | ||
[[Category: Immune system]] | [[Category: Immune system]] | ||