1omw: Difference between revisions

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-[[Image:1omw.png|left|200px]]
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-The line below this paragraph, containing "STRUCTURE_1omw", creates the "Structure Box" on the page.
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 {{STRUCTURE_1omw|  PDB=1omw  |  SCENE=  }}
 ===Crystal Structure of the complex between G Protein-Coupled Receptor Kinase 2 and Heterotrimeric G Protein beta 1 and gamma 2 subunits===
+{{ABSTRACT_PUBMED_12764189}}
+==Function==
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+[[http://www.uniprot.org/uniprot/ARBK1_BOVIN ARBK1_BOVIN]] Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner (By similarity). [[http://www.uniprot.org/uniprot/GBG2_BOVIN GBG2_BOVIN]] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. [[http://www.uniprot.org/uniprot/GBB1_BOVIN GBB1_BOVIN]] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
-The line below this paragraph, {{ABSTRACT_PUBMED_12764189}}, adds the Publication Abstract to the page
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-{{ABSTRACT_PUBMED_12764189}}
 ==About this Structure==
 [[1omw]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OMW OCA].
+==See Also==
+*[[Guanine nucleotide-binding protein|Guanine nucleotide-binding protein]]
 ==Reference==
-<ref group="xtra">PMID:012764189</ref><references group="xtra"/>
+<ref group="xtra">PMID:012764189</ref><references group="xtra"/><references/>
 [[Category: Bos taurus]]
 [[Category: Capel, W D.]]