1b4k: Difference between revisions

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[[Image:1b4k.png|left|200px]]
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{{STRUCTURE_1b4k|  PDB=1b4k  |  SCENE=  }}  
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===High resolution crystal structure of a MG2-dependent 5-aminolevulinic acid dehydratase===
===High resolution crystal structure of a MG2-dependent 5-aminolevulinic acid dehydratase===
{{ABSTRACT_PUBMED_10356331}}


 
==Function==
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[[http://www.uniprot.org/uniprot/HEM2_PSEAE HEM2_PSEAE]] Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).
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{{ABSTRACT_PUBMED_10356331}}


==About this Structure==
==About this Structure==
[[1b4k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B4K OCA].  
[[1b4k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B4K OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:010356331</ref><references group="xtra"/>
<ref group="xtra">PMID:010356331</ref><references group="xtra"/><references/>
[[Category: Porphobilinogen synthase]]
[[Category: Porphobilinogen synthase]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseae]]
[[Category: Frankenberg, N.]]
[[Category: Frankenberg, N.]]
[[Category: Heinz, D W.]]
[[Category: Heinz, D W.]]

Revision as of 09:41, 10 April 2014

Template:STRUCTURE 1b4k

High resolution crystal structure of a MG2-dependent 5-aminolevulinic acid dehydrataseHigh resolution crystal structure of a MG2-dependent 5-aminolevulinic acid dehydratase

Template:ABSTRACT PUBMED 10356331

FunctionFunction

[HEM2_PSEAE] Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).

About this StructureAbout this Structure

1b4k is a 2 chain structure with sequence from Pseae. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Frankenberg N, Erskine PT, Cooper JB, Shoolingin-Jordan PM, Jahn D, Heinz DW. High resolution crystal structure of a Mg2+-dependent porphobilinogen synthase. J Mol Biol. 1999 Jun 11;289(3):591-602. PMID:10356331 doi:10.1006/jmbi.1999.2808

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