4nc5: Difference between revisions

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{{STRUCTURE_4nc5|  PDB=4nc5  |  SCENE=  }}  
{{STRUCTURE_4nc5|  PDB=4nc5  |  SCENE=  }}  
===Human sialidase 2 in complex with 2,3-difluorosialic acid (covalent intermediate)===
===Human sialidase 2 in complex with 2,3-difluorosialic acid (covalent intermediate)===
{{ABSTRACT_PUBMED_24591206}}


==Function==
==Function==
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==About this Structure==
==About this Structure==
[[4nc5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NC5 OCA].  
[[4nc5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NC5 OCA].  
 
==See Also==
*[[Neuraminidase|Neuraminidase]]
 
==Reference==
<ref group="xtra">PMID:024591206</ref><references group="xtra"/><references/>
[[Category: Exo-alpha-sialidase]]
[[Category: Exo-alpha-sialidase]]
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Buchini, S.]]
[[Category: Buchini, S.]]
[[Category: Chavas, L M.G.]]
[[Category: Chavas, L M.G.]]

Revision as of 10:09, 2 April 2014

Template:STRUCTURE 4nc5

Human sialidase 2 in complex with 2,3-difluorosialic acid (covalent intermediate)Human sialidase 2 in complex with 2,3-difluorosialic acid (covalent intermediate)

Template:ABSTRACT PUBMED 24591206

FunctionFunction

[NEUR2_HUMAN] Hydrolyzes sialylated compounds.

About this StructureAbout this Structure

4nc5 is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Buchini S, Gallat FX, Greig IR, Kim JH, Wakatsuki S, Chavas LM, Withers SG. Tuning mechanism-based inactivators of neuraminidases: mechanistic and structural insights. Angew Chem Int Ed Engl. 2014 Mar 24;53(13):3382-6. doi: 10.1002/anie.201309675., Epub 2014 Mar 3. PMID:24591206 doi:http://dx.doi.org/10.1002/anie.201309675

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