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{{STRUCTURE_4kas| PDB=4kas | SCENE= }} | |||
===Crystal structure of FDTS from T. maritima mutant (H53D) with FAD and dUMP=== | |||
{{ABSTRACT_PUBMED_24563811}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/THYX_THEMA THYX_THEMA]] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate. | |||
==About this Structure== | |||
[[4kas]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KAS OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024563811</ref><references group="xtra"/><references/> | |||
[[Category: Mathews, I I.]] | |||
[[Category: Convertion of dump to dtmp using tetrahydrofolate]] | |||
[[Category: Dump]] | |||
[[Category: Fad]] | |||
[[Category: Fdt]] | |||
[[Category: Novel fdts fold]] | |||
[[Category: Thyx]] | |||
[[Category: Transferase]] |
Revision as of 12:24, 26 March 2014
Crystal structure of FDTS from T. maritima mutant (H53D) with FAD and dUMPCrystal structure of FDTS from T. maritima mutant (H53D) with FAD and dUMP
Template:ABSTRACT PUBMED 24563811
FunctionFunction
[THYX_THEMA] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate.
About this StructureAbout this Structure
4kas is a 4 chain structure. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Mathews II. Flavin-Dependent Thymidylate Synthase as a Drug Target for Deadly Microbes: Mutational Study and a Strategy for Inhibitor Design. J Bioterror Biodef. 2013 Apr 20;Suppl 12:004. PMID:24563811 doi:http://dx.doi.org/10.4172/2157-2526.S12-004