4kas: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4kas|  PDB=4kas  |  SCENE=  }}
===Crystal structure of FDTS from T. maritima mutant (H53D) with FAD and dUMP===
{{ABSTRACT_PUBMED_24563811}}


The entry 4kas is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/THYX_THEMA THYX_THEMA]] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate.


Authors: Mathews, I.I.
==About this Structure==
[[4kas]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KAS OCA].  


Description: Crystal structure of FDTS from T. maritima mutant (H53D) with FAD and dUMP
==Reference==
<ref group="xtra">PMID:024563811</ref><references group="xtra"/><references/>
[[Category: Mathews, I I.]]
[[Category: Convertion of dump to dtmp using tetrahydrofolate]]
[[Category: Dump]]
[[Category: Fad]]
[[Category: Fdt]]
[[Category: Novel fdts fold]]
[[Category: Thyx]]
[[Category: Transferase]]

Revision as of 12:24, 26 March 2014

Template:STRUCTURE 4kas

Crystal structure of FDTS from T. maritima mutant (H53D) with FAD and dUMPCrystal structure of FDTS from T. maritima mutant (H53D) with FAD and dUMP

Template:ABSTRACT PUBMED 24563811

FunctionFunction

[THYX_THEMA] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate.

About this StructureAbout this Structure

4kas is a 4 chain structure. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Mathews II. Flavin-Dependent Thymidylate Synthase as a Drug Target for Deadly Microbes: Mutational Study and a Strategy for Inhibitor Design. J Bioterror Biodef. 2013 Apr 20;Suppl 12:004. PMID:24563811 doi:http://dx.doi.org/10.4172/2157-2526.S12-004

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