4ojt: Difference between revisions
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{{STRUCTURE_4ojt| PDB=4ojt | SCENE= }} | |||
===Helicobacter pylori MTAN complexed with S-ribosylhomocysteine and adenine=== | |||
{{ABSTRACT_PUBMED_23148563}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/MTNN_HELPJ MTNN_HELPJ]] Responsible for cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) (By similarity). | |||
==About this Structure== | |||
[[4ojt]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OJT OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023148563</ref><references group="xtra"/><references/> | |||
[[Category: Adenosylhomocysteine nucleosidase]] | |||
[[Category: Mishra, V.]] | |||
[[Category: Ronning, D R.]] | |||
[[Category: Homodimer]] | |||
[[Category: Hydrolase]] | |||
Revision as of 12:21, 26 March 2014
Helicobacter pylori MTAN complexed with S-ribosylhomocysteine and adenineHelicobacter pylori MTAN complexed with S-ribosylhomocysteine and adenine
Template:ABSTRACT PUBMED 23148563
FunctionFunction
[MTNN_HELPJ] Responsible for cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) (By similarity).
About this StructureAbout this Structure
4ojt is a 1 chain structure. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Mishra V, Ronning DR. Crystal structures of the Helicobacter pylori MTAN enzyme reveal specific interactions between S-adenosylhomocysteine and the 5'-alkylthio binding subsite. Biochemistry. 2012 Dec 4;51(48):9763-72. doi: 10.1021/bi301221k. Epub 2012 Nov, 20. PMID:23148563 doi:http://dx.doi.org/10.1021/bi301221k