JMS/sandbox15: Difference between revisions
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<StructureSection load='1mbn' size='350' side='right' caption='myoglobin (PDB entry [[1mbn]])' scene='57/575026/Electrostatics/10'> | <StructureSection load='1mbn' size='350' side='right' caption='myoglobin (PDB entry [[1mbn]])' scene='57/575026/Electrostatics/10'> | ||
==Molecular Tour== | ===Molecular Tour=== | ||
The ability of increasing net charge to enable higher solubility is a known phenomenon<ref>doi: 10.1073/pnas.0402797101</ref>, and this study is consistent with previous reports<ref>PMID: 14741208</ref>. The aquatic animals have increased their net charge in a variety of ways - different combinations of amino acids switches. We present one such manifestation of this overall trend, by comparing the elephant and whale myoglobin structures. | The ability of increasing net charge to enable higher solubility is a known phenomenon<ref>doi: 10.1073/pnas.0402797101</ref>, and this study is consistent with previous reports<ref>PMID: 14741208</ref>. The aquatic animals have increased their net charge in a variety of ways - different combinations of amino acids switches. We present one such manifestation of this overall trend, by comparing the elephant and whale myoglobin structures. | ||
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</StructureSection> | </StructureSection> | ||
=== Modest increase in net charge contributes about the same as the enormous difference in body mass to the maximum time underwater === | === Modest increase in net charge contributes about the same as the enormous difference in body mass to the maximum time underwater === |