4jyt: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4jyt|  PDB=4jyt  |  SCENE=  }}
===Crystal Structure of Matriptase in complex with Inhibitor===


The entry 4jyt is ON HOLD
==Disease==
[[http://www.uniprot.org/uniprot/ST14_HUMAN ST14_HUMAN]] Defects in ST14 are a cause of ichthyosis autosomal recessive with hypotrichosis (ARIH) [MIM:[http://omim.org/entry/610765 610765]]. ARIH is a skin disorder characterized by congenital ichthyosis associated with the presence of less than the normal amount of hair.<ref>PMID:17273967</ref> 


Authors: Subramanya, H.S., Ravi, B.C., Ashok, K.N., Chakshusmathi, G., Ramesh, K.S.
==Function==
[[http://www.uniprot.org/uniprot/ST14_HUMAN ST14_HUMAN]] Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site.  


Description: Crystal Structure of Matriptase in complex with Inhibitor
==About this Structure==
[[4jyt]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JYT OCA].
 
==Reference==
<references group="xtra"/><references/>
[[Category: Matriptase]]
[[Category: Ashok, K N.]]
[[Category: Chakshusmathi, G.]]
[[Category: Ramesh, K S.]]
[[Category: Ravi, B C.]]
[[Category: Subramanya, H S.]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Matriptase]]

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