4o7c: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4o7c|  PDB=4o7c  |  SCENE=  }}
===Crystal structure of the first bromodomain of human BRD4 in complex with SB-614067-R===
{{ABSTRACT_PUBMED_24568369}}


The entry 4o7c is ON HOLD until Paper Publication
==Disease==
[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>  


Authors: Ember, S.W., Zhu, J.-Y., Watts, C., Schonbrunn, E.
==Function==
[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).  


Description:
==About this Structure==
[[4o7c]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O7C OCA].
 
==Reference==
<ref group="xtra">PMID:024568369</ref><references group="xtra"/><references/>
[[Category: Ember, S W.]]
[[Category: Schonbrunn, E.]]
[[Category: Watts, C.]]
[[Category: Zhu, J Y.]]
[[Category: Bromodomain]]
[[Category: Cap]]
[[Category: Cell cycle]]
[[Category: Hunk1]]
[[Category: Inhibitor]]
[[Category: Mcap]]
[[Category: Mitotic chromosome associated protein]]
[[Category: Protein binding-inhibitor complex]]
[[Category: Transcription-inhibitor complex]]

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