4hoe: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-'''Unreleased structure'''
+{{STRUCTURE_4hoe|  PDB=4hoe  |  SCENE=  }}
+===Candida albicans dihydrofolate reductase complexed with NADPH and 5-[3-(2,5-dimethoxy-4-phenylphenyl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine (UCP111E)===
+{{ABSTRACT_PUBMED_24568657}}
-The entry 4hoe is ON HOLD  until Mar 15 2015
+==Function==
+[[http://www.uniprot.org/uniprot/DYR_CANAX DYR_CANAX]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
-Authors: Paulsen, J.L., Anderson, A.C.
+==About this Structure==
+[[4hoe]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HOE OCA].
-Description: Candida albicans dihydrofolate reductase complexed with NADPH and 5-[3-(2,5-dimethoxy-4-phenylphenyl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine (UCP111E)
+==Reference==
+<ref group="xtra">PMID:024568657</ref><references group="xtra"/><references/>
+[[Category: Dihydrofolate reductase]]
+[[Category: Anderson, A C.]]
+[[Category: Paulsen, J L.]]
+[[Category: Antifungal agent]]
+[[Category: Candida albican]]
+[[Category: Drug design]]
+[[Category: Enzyme inhibitor]]
+[[Category: Fungal protein]]
+[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
+[[Category: Structure-activity relationship]]
+[[Category: Tetrahydrofolate dehydrogenase]]