4n0d: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4n0d|  PDB=4n0d  |  SCENE=  }}
===Crystal structure of the K345L variant of the Gi alpha1 subunit bound to GTPgammaS===


The entry 4n0d is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/GNAI1_RAT GNAI1_RAT]] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:16870394</ref> 


Authors: Thaker, T.M., Preininger, A.M., Sarwar, M., Hamm, H.E., Iverson, T.M.
==About this Structure==
[[4n0d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N0D OCA].  


Description: Crystal structure of the K345L variant of the Gi alpha1 subunit bound to GTPgammaS
==Reference==
<references group="xtra"/><references/>
[[Category: Heterotrimeric G-protein GTPase]]
[[Category: Hamm, H E.]]
[[Category: Iverson, T M.]]
[[Category: Preininger, A M.]]
[[Category: Sarwar, M.]]
[[Category: Thaker, T M.]]
[[Category: Gdp]]
[[Category: Gtp]]
[[Category: Guanine nucleotide binding protein]]
[[Category: Hydrolase]]
[[Category: Magnesium binding]]
[[Category: Rossman fold]]

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