Galactose-binding lectin

<StructureSection load='1v6i' size='350' side='right' caption='Structure of peanut galactose-binding lectin tetramer complex with β-D-galactose, α-D-glucose, Ca+2 (green) and Mn+2 (purple) ions (PDB entry 1v6i)' scene=>

Galactose-binding lectin (GBL) is a lectin which binds the carbohydrate sequence Gal-β(1,3)-GalNac. GBL is an all beta-sheet protein. GBL is used in affinity columns for capturing proteins which are glycosylated with Gal-β(1,3)-GalNac.

3D structures of galactose-binding lectin3D structures of galactose-binding lectin

Updated on 10-March-2014

Peanut GBL

1cq9, 1v6m, 1v6n, 1v6o, 2dh1, 2dvf – GBL

Peanut GBL binary complex

1qf3 – GBL + methyl-β-galactose
2dv9, 2dvd – GBL + β-D-galactose
1rir – GBL + porphyrin derivative

Peanut GBL ternary complex

1v6i, 1v6j, 1v6k, 1cr7, 2dvg – GBL + β-D-galactose + α-D-glucose
2pel – GBL + β-lactose + α-lactose
2tep, 2dva, 2dvb – GBL + β-D-galactose + N-acetyl-D-galactosamine
1ciw – GBL + β-D-galactose + 2-acetylamino-2-deoxy-D-glucopyranose
1rit – GBL + porphyrin derivative + β-lactose

Peanut GBL quaternary complex

1bzw, 1v6l – GBL + β-D-galactose + α-D-glucose + β-D-glucose

Pseudomonas aeruginosa GBL

1l7l, 1uoj – GBL

PsGBL binary complex

2wyf – GBL + methyl-β-galactose
4ljh – GBL + β-D-galactose
3zyf, 4a6s – GBL + galactopyranose derivative

PsGBL ternary complex

3zyh – GBL + galactopyranose derivative + gal-lys-pro-leu
3zyb – GBL + β-D-galactose + gal-lys-pro-leu
4lk6 – GBL + β-D-galactose + chlorophenol red
4lk7 – GBL + β-D-galactose + resorufin
1oko – GBL + β-D-galactose + α-D-galactose
4al9 – GBL + α-D-galactose + α-D-glucose

PsGBL quaternary complex

2vxj – GBL + β-D-galactose + α-D-galactose + α-D-glucose + β-D-glucose

2dry – LtGBL C terminal (mutant) – Lumbricus terrestris
2rst – LtGBL C terminal
2drz – LtGBL C terminal (mutant) + lactose
2zqn – LtGBL C terminal + lactose
2ds0 – LtGBL C terminal (mutant) + sialyllactose
2zqo – LtGBL C terminal + GalNac