4lm3: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-'''Unreleased structure'''
+{{STRUCTURE_4lm3|  PDB=4lm3  |  SCENE=  }}
+===Crystal structure of PDE10A2 with fragment ZT464===
+{{ABSTRACT_PUBMED_24375910}}
-The entry 4lm3 is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/PDE10_HUMAN PDE10_HUMAN]] Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate.<ref>PMID:17389385</ref>
-Authors: Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V.
+==About this Structure==
+[[4lm3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LM3 OCA].
-Description: Crystal structure of PDE10A2 with fragment ZT464
+==Reference==
+<ref group="xtra">PMID:024375910</ref><references group="xtra"/><references/>
+[[Category: Badger, J.]]
+[[Category: Chie-Leon, B.]]
+[[Category: Logan, C.]]
+[[Category: Nienaber, V.]]
+[[Category: Sridhar, V.]]
+[[Category: Fragment screening]]
+[[Category: Hydrolase]]
+[[Category: Hydrolase-hydrolase inhibitor complex]]