4lae: Difference between revisions
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{{STRUCTURE_4lae| PDB=4lae | SCENE= }} | |||
===Structure-Based Design of New Dihydrofolate Reductase Antibacterial Agents: 7-(Benzimidazol-1-yl)-2,4-diaminoquinazolines=== | |||
{{ABSTRACT_PUBMED_24428639}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DYR_STAAU DYR_STAAU]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | |||
==About this Structure== | |||
[[4lae]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LAE OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024428639</ref><references group="xtra"/><references/> | |||
[[Category: Dihydrofolate reductase]] | |||
[[Category: Hilgers, M T.]] | |||
[[Category: Dhfr]] | |||
[[Category: Folate]] | |||
[[Category: Nadph]] | |||
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | |||
[[Category: Protein-inhibitor complex]] |