4bpl: Difference between revisions
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{{STRUCTURE_4bpl| PDB=4bpl | SCENE= }} | |||
===rice importin_alpha in complex with nucleoplasmin NLS=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/IMA1A_ORYSJ IMA1A_ORYSJ]] Functions in nuclear protein import. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope.<ref>PMID:9727027</ref> <ref>PMID:11124253</ref> | |||
==About this Structure== | |||
[[4bpl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BPL OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024503158</ref><references group="xtra"/><references/> | |||
[[Category: Chang, C W.]] | |||
[[Category: Counago, R M.]] | |||
[[Category: Kobe, B.]] | |||
[[Category: Williams, S J.]] | |||
[[Category: Nuclear import]] | |||
[[Category: Nuclear localization signal]] | |||
[[Category: Transport protein]] | |||
Revision as of 20:18, 19 February 2014
rice importin_alpha in complex with nucleoplasmin NLSrice importin_alpha in complex with nucleoplasmin NLS
FunctionFunction
[IMA1A_ORYSJ] Functions in nuclear protein import. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope.[1] [2]
About this StructureAbout this Structure
4bpl is a 2 chain structure. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Chang CW, Williams SJ, Counago RM, Kobe B. Structural Basis of Interaction of Bipartite Nuclear Localization Signal from Agrobacterium VirD2 with Rice Importin-alpha Mol Plant. 2014 Feb 6. PMID:24503158 doi:http://dx.doi.org/10.1093/mp/ssu014
- ↑ Jiang CJ, Imamoto N, Matsuki R, Yoneda Y, Yamamoto N. Functional characterization of a plant importin alpha homologue. Nuclear localization signal (NLS)-selective binding and mediation of nuclear import of nls proteins in vitro. J Biol Chem. 1998 Sep 11;273(37):24083-7. PMID:9727027
- ↑ Jiang CJ, Shoji K, Matsuki R, Baba A, Inagaki N, Ban H, Iwasaki T, Imamoto N, Yoneda Y, Deng XW, Yamamoto N. Molecular cloning of a novel importin alpha homologue from rice, by which constitutive photomorphogenic 1 (COP1) nuclear localization signal (NLS)-protein is preferentially nuclear imported. J Biol Chem. 2001 Mar 23;276(12):9322-9. Epub 2000 Dec 20. PMID:11124253 doi:http://dx.doi.org/10.1074/jbc.M006430200