4ldw: Difference between revisions
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{{STRUCTURE_4ldw| PDB=4ldw | SCENE= }} | |||
===Crystal structure of the DNA Binding Domain of arabidopsis thaliana auxin response factor 1, P21 structure=== | |||
{{ABSTRACT_PUBMED_24485461}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ARFA_ARATH ARFA_ARATH]] Auxin response factors (ARFs) are transcriptional factors that binds specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Promotes flowering, stamen development, floral organ abscission and fruit dehiscence. Acts as repressor of IAA2, IAA3 and IAA7.<ref>PMID:12036261</ref> <ref>PMID:16176952</ref> | |||
==About this Structure== | |||
[[4ldw]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LDW OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024485461</ref><references group="xtra"/><references/> | |||
[[Category: Coll, M.]] | |||
[[Category: Boer, D R.]] | |||
[[Category: Dna binding]] | |||
[[Category: Nucleus]] | |||
[[Category: Transcription]] | |||
[[Category: Transcription factor]] | |||
Revision as of 08:03, 13 February 2014
Crystal structure of the DNA Binding Domain of arabidopsis thaliana auxin response factor 1, P21 structureCrystal structure of the DNA Binding Domain of arabidopsis thaliana auxin response factor 1, P21 structure
Template:ABSTRACT PUBMED 24485461
FunctionFunction
[ARFA_ARATH] Auxin response factors (ARFs) are transcriptional factors that binds specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Promotes flowering, stamen development, floral organ abscission and fruit dehiscence. Acts as repressor of IAA2, IAA3 and IAA7.[1] [2]
About this StructureAbout this Structure
4ldw is a 2 chain structure. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Boer DR, Freire-Rios A, van den Berg WA, Saaki T, Manfield IW, Kepinski S, Lopez-Vidrieo I, Franco-Zorrilla JM, de Vries SC, Solano R, Weijers D, Coll M. Structural Basis for DNA Binding Specificity by the Auxin-Dependent ARF Transcription Factors. Cell. 2014 Jan 30;156(3):577-89. doi: 10.1016/j.cell.2013.12.027. PMID:24485461 doi:http://dx.doi.org/10.1016/j.cell.2013.12.027
- ↑ Hagen G, Guilfoyle T. Auxin-responsive gene expression: genes, promoters and regulatory factors. Plant Mol Biol. 2002 Jun-Jul;49(3-4):373-85. PMID:12036261
- ↑ Ellis CM, Nagpal P, Young JC, Hagen G, Guilfoyle TJ, Reed JW. AUXIN RESPONSE FACTOR1 and AUXIN RESPONSE FACTOR2 regulate senescence and floral organ abscission in Arabidopsis thaliana. Development. 2005 Oct;132(20):4563-74. Epub 2005 Sep 21. PMID:16176952 doi:http://dx.doi.org/dev.02012