4lov: Difference between revisions
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{{STRUCTURE_4lov| PDB=4lov | SCENE= }} | |||
===Crystal structure of FimH in complex with Heptylmannoside=== | |||
{{ABSTRACT_PUBMED_24476493}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. | |||
==About this Structure== | |||
[[4lov]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LOV OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024476493</ref><references group="xtra"/><references/> | |||
[[Category: Garcia-Pino, A.]] | |||
[[Category: Nuland, N van.]] | |||
[[Category: Vanwetswinkel, S.]] | |||
[[Category: Carbohydrate binding protein]] | |||
[[Category: Ig fold]] | |||
[[Category: Pilus subunit]] | |||
Revision as of 08:00, 13 February 2014
Crystal structure of FimH in complex with HeptylmannosideCrystal structure of FimH in complex with Heptylmannoside
Template:ABSTRACT PUBMED 24476493
FunctionFunction
[FIMH_ECOLI] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed.
About this StructureAbout this Structure
4lov is a 1 chain structure. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Vanwetswinkel S, Volkov AN, Sterckx YG, Garcia-Pino A, Buts L, Vranken WF, Bouckaert J, Roy R, Wyns L, van Nuland NA. Study of the Structural and Dynamic Effects in the FimH Adhesin upon alpha-d-Heptyl Mannose Binding. J Med Chem. 2014 Feb 7. PMID:24476493 doi:http://dx.doi.org/10.1021/jm401666c