4cgx: Difference between revisions
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{{STRUCTURE_4cgx| PDB=4cgx | SCENE= }} | |||
===Crystal structure of the N-terminal domain of the PA subunit of Thogoto virus polymerase (form 1)=== | |||
{{ABSTRACT_PUBMED_24454773}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/PA_THOGV PA_THOGV]] Initiates transcription by a unique cap-stealing mechanism that involves the cleavage of only the m(7)GpppAm structure from cellular hnRNAs. | |||
==About this Structure== | |||
[[4cgx]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CGX OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024454773</ref><references group="xtra"/><references/> | |||
[[Category: Bouvier, D.]] | |||
[[Category: Crepin, T.]] | |||
[[Category: Cusack, S.]] | |||
[[Category: Guilligay, D.]] | |||
[[Category: Kadlec, J.]] | |||
[[Category: Kochs, G.]] | |||
[[Category: Lunardi, T.]] | |||
[[Category: Ruigrok, R W.H.]] | |||
[[Category: Transcription]] |
Revision as of 14:12, 5 February 2014
Crystal structure of the N-terminal domain of the PA subunit of Thogoto virus polymerase (form 1)Crystal structure of the N-terminal domain of the PA subunit of Thogoto virus polymerase (form 1)
Template:ABSTRACT PUBMED 24454773
FunctionFunction
[PA_THOGV] Initiates transcription by a unique cap-stealing mechanism that involves the cleavage of only the m(7)GpppAm structure from cellular hnRNAs.
About this StructureAbout this Structure
4cgx is a 2 chain structure. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Guilligay D, Kadlec J, Crepin T, Lunardi T, Bouvier D, Kochs G, Ruigrok RW, Cusack S. Comparative structural and functional analysis of orthomyxovirus polymerase cap-snatching domains. PLoS One. 2014 Jan 15;9(1):e84973. doi: 10.1371/journal.pone.0084973. eCollection, 2014 Jan 15. PMID:24454773 doi:http://dx.doi.org/10.1371/journal.pone.0084973