4lbn: Difference between revisions

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OCA

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-'''Unreleased structure'''
+{{STRUCTURE_4lbn|  PDB=4lbn  |  SCENE=  }}
+===Crystal structure of Human galectin-3 CRD in complex with LNnT===
+{{ABSTRACT_PUBMED_24326249}}
-The entry 4lbn is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/LEG3_HUMAN LEG3_HUMAN]] Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.<ref>PMID:15181153</ref> <ref>PMID:19594635</ref> <ref>PMID:19616076</ref>
-Authors: Collins, P.M., Blanchard, H.
+==About this Structure==
+[[4lbn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LBN OCA].
-Description: Crystal structure of Human galectin-3 CRD in complex with LNnT
+==Reference==
+<ref group="xtra">PMID:024326249</ref><references group="xtra"/><references/>
+[[Category: Blanchard, H.]]
+[[Category: Collins, P M.]]
+[[Category: Beta sandwich]]
+[[Category: Carbohydrate binding protein]]
+[[Category: Carbohydrate-recognition]]
+[[Category: Galectin]]
+[[Category: Glycosphingolipid]]
+[[Category: Lnnt]]
+[[Category: Sugar binding protein]]