4n06: Difference between revisions
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{{STRUCTURE_4n06| PDB=4n06 | SCENE= }} | |||
===Crystal structure of Cas1 from Archaeoglobus fulgidus and its nucleolytic activity=== | |||
{{ABSTRACT_PUBMED_24211577}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CAS1A_ARCFU CAS1A_ARCFU]] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity). | |||
==About this Structure== | |||
[[4n06]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N06 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024211577</ref><references group="xtra"/><references/> | |||
[[Category: Archaeoglobus fulgidus]] | |||
[[Category: Kim, J S.]] | |||
[[Category: Kim, T Y.]] | |||
[[Category: Shin, M.]] | |||
[[Category: Yen, L H.T.]] | |||
[[Category: Hydrolase]] |