Sandbox Reserved 822: Difference between revisions
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For binding of PtdIns(3,4,5)P<sub>3</sub> no significant conformational changes could be observed. Only <scene name='56/568020/Lys467/1'>Lys467</scene> occupies the position of the inositol ring in the absence of ligand and rotates to a position to contact the D5-phophate upon ligand binding. <ref name="Structural" /> | For binding of PtdIns(3,4,5)P<sub>3</sub> no significant conformational changes could be observed. Only <scene name='56/568020/Lys467/1'>Lys467</scene> occupies the position of the inositol ring in the absence of ligand and rotates to a position to contact the D5-phophate upon ligand binding. <ref name="Structural" /> | ||