Sandbox Reserved 818: Difference between revisions
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==Toxin entry and trafficking in target cells== | ==Toxin entry and trafficking in target cells== | ||
After binding to the target cell receptors, PTX enters the cells via receptor mediated endocytosis, and then follows the retrograde transport system, involving both the Golgi apparatus and the endoplasmic reticulum | After binding to the target cell receptors, PTX enters the cells via receptor mediated endocytosis, and then follows the ''retrograde transport system'', involving both the Golgi apparatus and the endoplasmic reticulum | ||
<ref name="Schmidt MA (1997)"> | <ref name="Schmidt MA (1997)"> | ||
El Baya, A., Linnemann, R., von Olleschik-Elbheim, L., Robenek, H., & Schmidt, M. A. (1997). Endocytosis and retrograde transport of pertussis toxin to the Golgi complex as a prerequisite for cellular intoxication. European journal of cell biology, 73(1), 40. | El Baya, A., Linnemann, R., von Olleschik-Elbheim, L., Robenek, H., & Schmidt, M. A. (1997). Endocytosis and retrograde transport of pertussis toxin to the Golgi complex as a prerequisite for cellular intoxication. European journal of cell biology, 73(1), 40. | ||