4lnq: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-'''Unreleased structure'''
+{{STRUCTURE_4lnq|  PDB=4lnq  |  SCENE=  }}
+===Crystal structure of Ifi202 HINa domain in complex with 20bp dsDNA===
-The entry 4lnq is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/IFI2_MOUSE IFI2_MOUSE]] Inhibits the transcriptional activity of several transcription factors, including NF-kappa-B p50 and p65, FOS, JUN, E2F1, E2F4, MYOD1 and myogenin. Has anti-apoptotic effects due to inhibition of the transcriptional activity of p53. Binds dsDNA in the cytosol. Is involved in innate immune response and has anti-inflammatory activity. Inhibits caspase activation in response to cytosolic DNA and may inhibit the activation of the AIM2 inflammasome, probably via association with AIM2.<ref>PMID:16670293</ref> <ref>PMID:19131592</ref>
-Authors: Li, H., Wang, Z.-X., Wu, J.-W.
+==About this Structure==
+[[4lnq]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LNQ OCA].
-Description: Crystal structure of Ifi202 HINa domain in complex with 20bp dsDNA
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Li, H.]]
+[[Category: Wang, Z X.]]
+[[Category: Wu, J W.]]
+[[Category: Dna binding]]
+[[Category: Dna binding protein-dna complex]]
+[[Category: Ob fold]]