Sandbox Reserved 825: Difference between revisions

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[[Image:FRB Phosphatidic Acid.png|upright=1.25|right|thumb| Fig.2 A representative view of phosphatidic acid docked into its binding site on the FRB domain.]]
[[Image:FRB Phosphatidic Acid.png|upright=1.25|right|thumb| Fig.2 A representative view of phosphatidic acid docked into its binding site on the FRB domain.]]


The FRB domain is made up of an <scene name='56/568023/N-terminal_domain_of_frb/2'>N-terminal</scene> disordered domain and a four a-helices bundle joined by short loops (<scene name='56/568023/Helix_1/1'>a1</scene>, <scene name='56/568023/Helix_2/1'>a2</scene>, <scene name='56/568023/Helix_3/1'>a3</scene>, <scene name='56/568023/Helix_4/1'>a4</scene>). <ref> PMID: 17684489  </ref>
The FRB domain is made up of an <scene name='56/568023/N-terminal_domain_of_frb/2'>N-terminal</scene> disordered domain and a four α-helices bundle joined by short loops (<scene name='56/568023/Helix_1/1'>α1</scene>, <scene name='56/568023/Helix_2/1'>α2</scene>, <scene name='56/568023/Helix_3/1'>α3</scene>, <scene name='56/568023/Helix_4/1'>α4</scene>). <ref> PMID: 17684489  </ref>
Helix 3 contains a <scene name='56/568023/Helix_3_bend_residues/1'>bend</scene> of approximately 45° and its N-terminal half is largely disordered.
Helix 3 contains a <scene name='56/568023/Helix_3_bend_residues/1'>bend</scene> of approximately 45° and its N-terminal half is largely disordered.


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OCA, Dimitri Feltrin, Hamelin Baptiste