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[[ATPase]] is an enzyme which catalyzes the breakdown of ATP into ADP and a phosphate ion.  This dephosphorylation releases energy which the enzyme uses to drive other reactions. Vacuolar-type H+ ATPase (V-ATPase) couples the energy to proton transport across membranes. The images at the left and at the right correspond to one representative ATPase, ''i.e.'' the NMR structure of rat ATPase ([[1mo8]]).<br />
[[ATPase]] is an enzyme which catalyzes the breakdown of ATP into ADP and a phosphate ion.  This dephosphorylation releases energy which the enzyme uses to drive other reactions. Vacuolar-type H+ ATPase (V-ATPase) couples the energy to proton transport across membranes. ATPAse types include: '''F-ATPase''' - the prime producers of ATP; '''V-ATPase''' transport solutes; '''A-ATPase''' are found in archaea; '''P-ATPase''' transport ions; '''E-ATPase''' hydrolyze extracellular ATP. Vacuolar-type H+ ATPase couples the energy to proton transport across membranes. MipZ is an ATPase which forms a complex with the chromosome partitioning protein ParB and is responsible for the regulation of FtsZ ring formation.  ATPase domains include metal-binding domain (MBD) and nucleotide-binding domain (NBD). For more details see:<br />
*Details on Cu transporting ATPase are in [[P(1B)-Type Cu(I) Transporting ATPases ATP7A and ATP7B]].<br />
*Cu transporting ATPase are in [[P(1B)-Type Cu(I) Transporting ATPases ATP7A and ATP7B]].<br />
*Details on Na/K transporting ATPase are in [[Sodium-Potassium ATPase]].<br />
*Na/K transporting ATPase are in [[Sodium-Potassium ATPase]].<br />
*Details on Transitional endoplasmic reticulum ATPase are in [[Valosin Containing Protein D120]].
*Transitional endoplasmic reticulum ATPase are in [[Valosin Containing Protein D120]].<br />
*[[A-ATP Synthase]].


'''Structural and functional insights into a dodecameric molecular machine – The RuvBL1/RuvBL2 complex (ATPase)<ref >PMID: 21933716</ref>'''<br />
'''Structural and functional insights into a dodecameric molecular machine – The RuvBL1/RuvBL2 complex (ATPase)<ref >PMID: 21933716</ref>'''<br />
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}


=== Cu transporting ATPase ===
===F-ATPase===
 
''F1F0 ATPase α subunit''
 
[[2jmx]] - bF1-ATPS+subunit O<br />
[[2r9v]] - F1-ATPS – ''Thermotoga maritima''
 
''F1F0 ATPase β subunit''
 
[[1b9u]] – EcF1-ATPS membrane domain – ''Escherichia coli'' -NMR<BR />
[[1l2p]] – EcF1-ATPS dimerization domain<br />
[[2khk]] - EcF1-ATPS fragment – NMR<BR />
 
''F1F0 ATPase γ subunit''
 
[[1wu0]] – BsATPS – NMR<BR />
[[1a91]], [[1c0v]], [[1aty]], [[1c99]] - EcF1-ATPS – NMR<BR />
[[2wgm]], [[1yce]] – F0-ATPS – ''Ilyobacter tartaricus''<br />
[[2x2v]] – F0-ATPS – ''Bacillus pseudofirmus''<br />
 
''F1F0 ATPase δ subunit''
 
[[1abv]] – EcF1-ATPS N terminal – NMR<BR />
 
''F1F0 ATPase ε subunit''
 
[[2rq6]], [[2rq7]] - F1-ATPS – ''Thermosynechococcus elongatus''<br />
[[1abv]]– EcF1-ATPS (mutant)<br />
[[1bsh]], [[1bsn]] – EcF1-ATPS – NMR<BR />
[[2e5t]], [[2e5u]] – BsF1-ATPS C terminal – NMR<BR />
[[2e5y]] – BsF1-ATPS
 
''F1F0 ATPase α, β subunits''
 
[[1sky]] – BsF1-ATPS – Bacillus sp. Ps3
 
''F1F0 ATPase α, δ subunits''
 
[[2a7u]] – EcF1-ATPS N termini – NMR<BR />
 
''F1F0 ATPase β, δ subunits''
 
[[2cly]] – bF1-ATPS + ATPS coupling factor
 
''F1F0 ATPase γ, ε subunits''
 
[[1fs0]] – EcF1-ATPS
 
''F1F0 ATPase α, β, γ subunits''
 
[[1ohh]] – bF1-ATPS+ IF1 inhibitor – bovine<br />
[[1e1q]], [[2w6e]], [[2w6f]], [[2w6g]], [[2w6h]], [[2w6i]], [[2w6j]] - bF1-ATPS<br />
[[1e1r]] - bF1-ATPS+Mg+ADP+AlF4<br />
[[1w0j]], [[1w0k]] -  bF1-ATPS+BeF3<br />
[[1nbm]] -  bF1-ATPS+nitrobenzofurazan<br />
[[1mab]] - F1-ATPS – rat
 
''F1F0 ATPase α, β, γ, δ, ε subunits''
 
[[4asu]] - bF1-ATPS<br />
[[2v7q]] -  bF1-ATPS+inhibitor<br />
[[2xnd]], [[2xok]] - bF1-ATPS+ATPS lipid-binding protein<br />
[[2wpd]], [[2wss]] - yF1-ATPS+subunit 9+Mg+ADP+ATP<br />
[[3oe7]], [[3oee]], [[3oeh]], [[3ofn]] - yF1-ATPS (mutant)<br />
[[3fks]], [[3zry]] - yF1-ATPS<br />
[[3j0j]] – TtATPS α,β,γ,δ,ε,ζ - Cryo EM<br />
 
''F1F0 ATPase α, β, γ, ε subunits''
 
[[3oaa]] – EcF1-ATPS (mutant)<br />
[[1e79]] - bFF1-ATPS<br />
 
''F1F0 ATPase α,β,γ,δ,ε,9,B,D,6,O subunits''
 
[[4b2q]] – yATPase subunits α,β,γ,δ,ε +9,B,D,6,O – Cryo EM
 
[[1bmf]] - bF1-ATPS<br />
[[3dze]] – bF1-ATPS subunit S<br />
[[1cow]] - bF1-ATPS+aurovertin B
 
===V-ATPase===
 
''V-ATPase subunit A''
 
[[3i4l]] - PhATPS subunit A+AMPPNP<br />
[[3mfy]], [[3m4y]], [[3nd8]], [[3nd9]], [[3p20]], [[3qg1]], [[3qia]], [[3qjy]], [[3sdz]], [[3se0]] - PhATPS subunit A
mutant)<br />
[[3i72]], [[3i73]], [[3ikj]] - TtATPS subunit A (mutant)<br />
 
''V-ATPase subunit B''
 
[[2c61]] - MmATPS subunit B – ''Methanosarcina mazei''<br />
[[2rkw]], [[3b2q]], [[3ssa]], [[3tgw]], [[3tiv]] - MmATPS subunit B (mutant)<br />
[[3dsr]] - MmATPS subunit B+ADP<br />
[[3eiu]] - MmATPS subunit B+ATP<br />
 
''V-ATPase subunit C''
 
[[1u7l]], [[3u2f]], [[3u2y]], [[3u32]], [[3ud0]] - yATPS subunit C<br />
[[3v3c]] - ATPS subunit C - pea<br />
[[1ijp]], [[1l6t]] – EcF1-ATPS subunit C (mutant) – ''Escherichia coli'' - NMR<br />
[[1r5z]], [[1v9m]] - TtATPS subunit C – ''Thermus thermophilus''<br />
[[3lg8]] - MtATPS subunit C C-terminal<br />
[[2w5j]] - ATPS subunit C - spinach<br />
 
''V-ATPase subunit E''
 
[[2kz9]] – yATPase subunit E<br />
[[2dm9]], [[2dma]], [[4dt0]] - PhATPS subunit E – ''Pyrococcus horikoshii''<br />
[[2kk7]] - MjATPS subunit E – ''Methanocaldococcus jannaschii''<br />
[[3v6i]] – TtATPS subunit E + VAPC<br />
 
''V-ATPase subunit F''
 
[[2qai]] - ATPS subunit F – ''Pyrococcus furiosus''<br />
[[2i4r]] - ATPS subunit F – ''Archaeoglobus fulgidus''<br />
[[2ov6]] - MmATPS subunit F - NMR<br />
[[2d00]] - TtATPS subunit F <br />
[[4ix9]] – yATP subunit F (mutant)<br />
 
''V-ATPase subunit G''
 
[[2k88]] - yATPS subunit G - NMR<br />
 
''V-ATPase subunit H''
 
[[1ho8]] – yATPS subunit H – yeast<br />
 
''V-ATPase subunit K''
 
[[2bl2]], [[2cyd]] - ATPS subunit K – ''Enterococcus hirae''<br />
 
''V-ATPase subunit I''
 
[[3rrk]] – ATPS subunit I N terminal – ''Meiothermus ruber''
 
[[4dl0]], [[4efa]] - yATPase subunits C,G,E<br />
[[3w3a]] - yATPS subunit A,B,D,F<br />
[[3a5c]], [[3a5d]] - TtATPS subunit A,B,D,F<br />
[[3gqb]] - TtATPS subunit A (mutant),B (mutant)<br />
[[3k5b]] - TtATPS subunit E (mutant)+C<br />
===P-ATPase===
 
''Cu transporting ATPase''


[[2kmv]], [[2kmx]], [[2arf]] – hATPase NBD – human – NMR<br />
[[2kmv]], [[2kmx]], [[2arf]] – hATPase NBD – human – NMR<br />
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[[3rfu]] – ATPase – ''Legionella pneumophila''<br />
[[3rfu]] – ATPase – ''Legionella pneumophila''<br />
[[4f2f]] - ATPase metal-binding domain – ''Streptococcus pneumonia''<br />
[[4f2f]] - ATPase metal-binding domain – ''Streptococcus pneumonia''<br />
[[3j08]], [[3j09]] - AfATPase<br />
[[3a1c]] – AfATPase + AMPPCP<br />
[[3a1d]] - AfATPase + ADP-Mg<br / >
[[3a1e]] - AfATPase (mutant) + AMPPCP<br />


=== Na/K transporting ATPase ===
''Na/K transporting ATPase''


[[3a3y]] - SaATPase+K+ouabain – ''Squalus acanthias''<br />
[[3a3y]] - SaATPase+K+ouabain – ''Squalus acanthias''<br />
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[[2zxe]] - ATPase subunits α,β + phospholemman-like protein – spiny dogfish
[[2zxe]] - ATPase subunits α,β + phospholemman-like protein – spiny dogfish


=== Ca+2 transporting ATPase ===
''Ca+2 transporting ATPase''


[[3fgo]] - rATPase+CPA+AMPPCP – rabbit<br />
[[3fgo]] - rATPase+CPA+AMPPCP – rabbit<br />
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[[2by4]], [[2yfy]], [[3nal]], [[3nam]], [[3nan]] - rATPase HNE2 state+thapsigargin derivative
[[2by4]], [[2yfy]], [[3nal]], [[3nam]], [[3nan]] - rATPase HNE2 state+thapsigargin derivative


=== Zn+2 transporting ATPase ===
''Zn+2 transporting ATPase''


[[2ofg]], [[2ofh]] - sATPase N-terminal – NMR
[[2ofg]], [[2ofh]] - sATPase N-terminal – NMR


=== K+ transporting ATPase ===
''K+ transporting ATPase''


[[2a00]], [[2a29]] - EcATPase NBD of KdpB+AMPPNP– ''Escherichia coli'' – NMR<br />
[[2a00]], [[2a29]] - EcATPase NBD of KdpB+AMPPNP– ''Escherichia coli'' – NMR<br />
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[[2ynr]] – pATPase – Cryo EM
[[2ynr]] – pATPase – Cryo EM


=== As+ transporting ATPase ===
''As+ transporting ATPase''


[[1ii0]], [[1f48]] - EcATPase<br />
[[1ii0]], [[1f48]] - EcATPase<br />
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[[3ibg]] - ATPase GET3 – ''Aspergillus fumigatus''
[[3ibg]] - ATPase GET3 – ''Aspergillus fumigatus''


=== H+ transporting ATPase ===
''H+ transporting ATPase''


[[3b8c]]  - AtATPase C terminal truncated<br />
[[3b8c]]  - AtATPase C terminal truncated<br />
[[1mhs]] - ATPase – ''Neurospora crassa''<br />
[[1mhs]] - ATPase – ''Neurospora crassa''<br />


For yeast V-type ATPase see [[ATP synthase]].<br />
''Na+ transporting ATPase''
 
=== Na+ transporting ATPase ===


[[2db4]], [[3aou]] - EhATPase subunit K – ''Enterococcus hirae''<br />
[[2db4]], [[3aou]] - EhATPase subunit K – ''Enterococcus hirae''<br />
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[[1yce]] - ATPase rotor ring – ''Ilyobacter tartaricus''
[[1yce]] - ATPase rotor ring – ''Ilyobacter tartaricus''


=== H/K transporting ATPase ===
''H/K transporting ATPase''


[[1iwc]], [[1iwf]] - pATPase NBD <br />
[[1iwc]], [[1iwf]] - pATPase NBD <br />
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[[2xzb]] – pATPase subunits α, β<br />
[[2xzb]] – pATPase subunits α, β<br />


=== Mg+2 transporting ATPase ===
''Mg+2 transporting ATPase''


[[3gwi]] – EcATPase P-1 NBD
[[3gwi]] – EcATPase P-1 NBD


 
''Arg/ornithine transporting ATPase''
=== Arg/ornithine transporting ATPase ===


[[3md0]] – MtATPase+GDP – ''Mycobacterium tuberculosis''<br />
[[3md0]] – MtATPase+GDP – ''Mycobacterium tuberculosis''<br />
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[[1d8s]] – EcATPase F1<br />
[[1d8s]] – EcATPase F1<br />
[[1vdz]] – PhATPase subunit A – ''Pyrococcus horikoshii''<br />
[[1vdz]] – PhATPase subunit A – ''Pyrococcus horikoshii''<br />
===P-ATPase Cu transporting===
[[3j08]], [[3j09]] - AfATPase<br />
[[3a1c]] – AfATPase + AMPPCP<br />
[[3a1d]] - AfATPase + ADP-Mg<br / >
[[3a1e]] - AfATPase (mutant) + AMPPCP


===RNA-dependent ATPase===
===RNA-dependent ATPase===

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