Sandbox Reserved 827: Difference between revisions
Léa Faivre (talk | contribs) No edit summary |
Léa Faivre (talk | contribs) No edit summary |
||
Line 5: | Line 5: | ||
= Overall structure = | ==Your Heading Here (maybe something like 'Structure')==<StructureSection load='1dq8' size='500' side='right' caption='Structure of HMG-CoA reductase (PDB entry [[1dq8]])' scene=''>= Overall structure = | ||
<Structure load='4IW0' size='500' frame='true' align='right' caption='TBK1 monomer' scene='56/568025/Vide/1' /> | <Structure load='4IW0' size='500' frame='true' align='right' caption='TBK1 monomer' scene='56/568025/Vide/1' /> | ||
Line 40: | Line 40: | ||
'''Polyubiquitination :''' Polyubiquitination in a Lys63 manner on | '''Polyubiquitination :''' Polyubiquitination in a Lys63 manner on | ||
<scene name='56/568025/K30/1'>Lys30</scene> helps the activation of the kinase. The same type of modification on <scene name='56/568025/K401/1'>Lys401</scene> is responsible for dimerization. Type Lys48 polyubiquitination on Lys670 is done by DTX4 and is responsible for the degradation of the protein. | <scene name='56/568025/K30/1'>Lys30</scene> helps the activation of the kinase. The same type of modification on <scene name='56/568025/K401/1'>Lys401</scene> is responsible for dimerization. Type Lys48 polyubiquitination on Lys670 is done by DTX4 and is responsible for the degradation of the protein.</StructureSection> | ||
= Signalling pathways = | = Signalling pathways = |