Peptide: Difference between revisions
Eran Hodis (talk | contribs) No edit summary |
Eran Hodis (talk | contribs) No edit summary |
||
| Line 4: | Line 4: | ||
==Peptides & Backbones== | ==Peptides & Backbones== | ||
This is the <scene name='Peptide~Emartz_view1~3'>backbone</scene> of 1 amino acid. Adding to the backbone with an additional amino acid on each side gives a <scene name='Peptide~Emartz_view2~1'>tripeptide</scene> (3 amino acids). No side groups are shown, and most hydrogens are omitted. Now each amino acid has a 1 carbon side group so we have <scene name='Peptide~Emartz_view3~2'>Ala-Ala-Ala</scene> (tri-alanine). Adding a carbon chain plus an NH3 on the first amino acid gives <scene name='Peptide~Emartz_view4~4'>Lys-Ala-Ala</scene>. Adding <scene name='Peptide~Emartz_view5~3'>three more carbons</scene> to the 3rd amino acid gives [[isoleucine]]: Lys-Ala-Ile. The 4th amino acid is threonine with its hydroxyl, giving <scene name='Peptide~Emartz_view6~1'>Lys-Ala-Ile-Thr</scene>. Here is the shape of the <scene name='Peptide~Emartz_view7~1'>tetrapeptide</scene> (4 AAs). The stick representation has too much detail for larger proteins, so the α-carbons are connected with a line called the <scene name='Peptide~Emartz_view8~1'>backbone trace</scene>. Showing only the <scene name='Peptide~Emartz_view9~ | This is the <scene name='Peptide~Emartz_view1~3'>backbone</scene> of 1 amino acid. Adding to the backbone with an additional amino acid on each side gives a <scene name='Peptide~Emartz_view2~1'>tripeptide</scene> (3 amino acids). No side groups are shown, and most hydrogens are omitted. Now each amino acid has a 1 carbon side group so we have <scene name='Peptide~Emartz_view3~2'>Ala-Ala-Ala</scene> (tri-alanine). Adding a carbon chain plus an NH3 on the first amino acid gives <scene name='Peptide~Emartz_view4~4'>Lys-Ala-Ala</scene>. Adding <scene name='Peptide~Emartz_view5~3'>three more carbons</scene> to the 3rd amino acid gives [[isoleucine]]: Lys-Ala-Ile. The 4th amino acid is threonine with its hydroxyl, giving <scene name='Peptide~Emartz_view6~1'>Lys-Ala-Ile-Thr</scene>. Here is the shape of the <scene name='Peptide~Emartz_view7~1'>tetrapeptide</scene> (4 AAs). The stick representation has too much detail for larger proteins, so the α-carbons are connected with a line called the <scene name='Peptide~Emartz_view8~1'>backbone trace</scene>. Showing only the <scene name='Peptide~Emartz_view9~2'>backbone</scene> makes it easier to see the path of the protein chain (its secondary and tertiary structure). | ||
Revision as of 12:56, 11 October 2007
|
Peptides are chains of amino acids linked by peptide bonds. Long peptides, or polypeptides, are called proteins.
Peptides & BackbonesPeptides & Backbones
This is the of 1 amino acid. Adding to the backbone with an additional amino acid on each side gives a (3 amino acids). No side groups are shown, and most hydrogens are omitted. Now each amino acid has a 1 carbon side group so we have (tri-alanine). Adding a carbon chain plus an NH3 on the first amino acid gives . Adding to the 3rd amino acid gives isoleucine: Lys-Ala-Ile. The 4th amino acid is threonine with its hydroxyl, giving . Here is the shape of the (4 AAs). The stick representation has too much detail for larger proteins, so the α-carbons are connected with a line called the . Showing only the makes it easier to see the path of the protein chain (its secondary and tertiary structure).