4bub: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 2: | Line 2: | ||
===CRYSTAL STRUCTURE OF MURE LIGASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH ADP=== | ===CRYSTAL STRUCTURE OF MURE LIGASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH ADP=== | ||
{{ABSTRACT_PUBMED_23826965}} | {{ABSTRACT_PUBMED_23826965}} | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/MURE_THEMA MURE_THEMA]] Catalyzes the addition of both L- and D-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Is also able to use meso-diaminopimelate as the amino acid substrate in vitro, although much less efficiently.<ref>PMID:16595662</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[4bub]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[4bub]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BUB OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:023826965</ref><references group="xtra"/><references/> | <ref group="xtra">PMID:023826965</ref><references group="xtra"/><references/> | ||
[[Category: | [[Category: Atcc 43589]] | ||
[[Category: Contreras-Martel, C.]] | [[Category: Contreras-Martel, C.]] | ||
[[Category: Dessen, A.]] | [[Category: Dessen, A.]] | ||
Revision as of 11:07, 18 December 2013
CRYSTAL STRUCTURE OF MURE LIGASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH ADPCRYSTAL STRUCTURE OF MURE LIGASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH ADP
Template:ABSTRACT PUBMED 23826965
FunctionFunction
[MURE_THEMA] Catalyzes the addition of both L- and D-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Is also able to use meso-diaminopimelate as the amino acid substrate in vitro, although much less efficiently.[1]
About this StructureAbout this Structure
4bub is a 2 chain structure with sequence from Atcc 43589. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Favini-Stabile S, Contreras-Martel C, Thielens N, Dessen A. MreB and MurG as scaffolds for the cytoplasmic steps of peptidoglycan biosynthesis. Environ Microbiol. 2013 Jun 3. doi: 10.1111/1462-2920.12171. PMID:23826965 doi:10.1111/1462-2920.12171
- ↑ Boniface A, Bouhss A, Mengin-Lecreulx D, Blanot D. The MurE synthetase from Thermotoga maritima is endowed with an unusual D-lysine adding activity. J Biol Chem. 2006 Jun 9;281(23):15680-6. Epub 2006 Apr 4. PMID:16595662 doi:http://dx.doi.org/M506311200