Molecular Playground/Bacterial Chemotaxis Complex: Difference between revisions
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• <scene name='57/571407/Chea_p3p4p5/1'>CheA</scene> is a large 5-subdomain (P1-P5) histidine kinase that auto-phosphorylates depending on it's interaction with the receptor and localized concentrations of the response regulator protein CheY. This scene is of P3-P5 as a homo-dimer (1B3Q). For more information, see [http://proteopedia.org/wiki/index.php/Molecular_Playground/CheA CheA Molecular Playground page] | • <scene name='57/571407/Chea_p3p4p5/1'>CheA</scene> is a large 5-subdomain (P1-P5) histidine kinase that auto-phosphorylates depending on it's interaction with the receptor and localized concentrations of the response regulator protein CheY. This scene is of P3-P5 as a homo-dimer (1B3Q). For more information, see [http://proteopedia.org/wiki/index.php/Molecular_Playground/CheA CheA Molecular Playground page] | ||
• The small multi-functioning adaptor and scaffolding protein <scene name='57/571407/Chew/1'>CheW</scene> (2HO9) is not directly involved in the signaling event but is essential for CheA activity. | |||
• When combined, these three proteins assemble into large membrane associated complex primed for relaying signals from outside the cell. This scene illustrates the beginning of a larger hexagonal-like assembly of the complexes. Recent cryo-EM data shows evidence for extended hexagonal arrays. | |||