Molecular Playground/Bacterial Chemotaxis Complex: Difference between revisions

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• The <scene name='57/571407/Cytoplasmic_receptor/1'>chemoreceptor</scene> (1QU7) – also called methyl-accepting protein, MCP – is a ~380Å long, alpha helical homo-dimer with many domains. The <scene name='57/571407/Cytoplasmic_receptor/2'>signaling domain</scene> at the cytosplasmic tip is where both CheW and CheA interact and bind.  
• The <scene name='57/571407/Cytoplasmic_receptor/1'>chemoreceptor</scene> (1QU7) – also called methyl-accepting protein, MCP – is a ~380Å long, alpha helical homo-dimer with many domains. The <scene name='57/571407/Cytoplasmic_receptor/2'>signaling domain</scene> at the cytosplasmic tip is where both CheW and CheA interact and bind.  


• CheA is a large 5-subdomain (P1-P5) histidine kinase that auto-phosphorylates depending on it's interaction with the receptor and localized concentrations of the response regulator protein CheY.
<scene name='57/571407/Chea_p3p4p5/1'>CheA</scene> (1B3Q shows P3-P5 as a homodimer) is a large 5-subdomain (P1-P5) histidine kinase that auto-phosphorylates depending on it's interaction with the receptor and localized concentrations of the response regulator protein CheY.

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Elizabeth R. Haglin, Michal Harel, Maryam Kashefy