4jrk: Difference between revisions

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OCA

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-'''Unreleased structure'''
+{{STRUCTURE_4jrk|  PDB=4jrk  |  SCENE=  }}
+===Crystal Structure of Escherichia coli Hfq Surface Mutant===
+{{ABSTRACT_PUBMED_24288369}}
-The entry 4jrk is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/HFQ_ECOLI HFQ_ECOLI]] RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Involved in the regulation of stress responses mediated by the sigma factors RpoS, sigma-E and sigma-32. Binds with high specificity to tRNAs. In vitro, stimulates synthesis of long tails by poly(A) polymerase I. Required for RNA phage Qbeta replication.<ref>PMID:805130</ref> <ref>PMID:10677490</ref> <ref>PMID:11222598</ref> <ref>PMID:17158661</ref> <ref>PMID:19909729</ref>   Seems to play a role in persister cell formation; upon overexpression decreases persister cell formation while deletion increases persister formation.<ref>PMID:805130</ref> <ref>PMID:10677490</ref> <ref>PMID:11222598</ref> <ref>PMID:17158661</ref> <ref>PMID:19909729</ref>
-Authors: Robinson, K.E., Orans, J.
+==About this Structure==
+[[4jrk]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JRK OCA].
-Description: Crystal Structure of Escherichia coli Hfq Surface Mutant
+==Reference==
+<ref group="xtra">PMID:024288369</ref><references group="xtra"/><references/>
+[[Category: Orans, J.]]
+[[Category: Robinson, K E.]]
+[[Category: Post-transcriptional regulator]]
+[[Category: Riboregulator]]
+[[Category: Rna binding protein]]