User:Alisha, Deepa, Pamiz/Sandbox 1: Difference between revisions
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'''H+/K+-ATPase pump''' The signals (acetylcholine, histamine, and gastrin) activate the pump in order for the vesicles to move toward the lumen of the stomach.9 These signals bind to their corresponding receptors and activate the cAMP dependent pathway and the Ca2+ dependent pathway.9 Increased levels of intracellular Ca2+ and cAMP will promote the translocation of vesicles to the canalicular membrane, activating the H+/K+-ATPase.9 Histamine binds to a receptor (Histamine H2), and sends a signal through a G protein which activates adenylate cyclase, and catalyzes the conversion of ATP to cAMP.9 Gastrin will stimulate the release of histamine by binding to the gastrin receptor (CCK2).9 Acetylcholine binds to a receptor (Muscarinic M3) and releases Ca2+ from the endoplasmic reticulum.9]] | '''H+/K+-ATPase pump''' The signals (acetylcholine, histamine, and gastrin) activate the pump in order for the vesicles to move toward the lumen of the stomach.9 These signals bind to their corresponding receptors and activate the cAMP dependent pathway and the Ca2+ dependent pathway.9 Increased levels of intracellular Ca2+ and cAMP will promote the translocation of vesicles to the canalicular membrane, activating the H+/K+-ATPase.9 Histamine binds to a receptor (Histamine H2), and sends a signal through a G protein which activates adenylate cyclase, and catalyzes the conversion of ATP to cAMP.9 Gastrin will stimulate the release of histamine by binding to the gastrin receptor (CCK2).9 Acetylcholine binds to a receptor (Muscarinic M3) and releases Ca2+ from the endoplasmic reticulum.9]] | ||
[[Image:Signaling-pathway.gif]] | |||
== Esomeprazole Mechanism == | == Esomeprazole Mechanism == | ||