4lqd: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-'''Unreleased structure'''
+{{STRUCTURE_4lqd|  PDB=4lqd  |  SCENE=  }}
+===The crystal structures of the Brucella protein TcpB and the TLR adaptor protein TIRAP show structural differences in microbial TIR mimicry===
-The entry 4lqd is ON HOLD
+==Function==
+[[http://www.uniprot.org/uniprot/TIRAP_HUMAN TIRAP_HUMAN]] Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6.<ref>PMID:18292575</ref> <ref>PMID:19509286</ref>
-Authors: Snyder, G.A., Smith, P., Jiang, J., Xiao, T.S.
+==About this Structure==
+[[4lqd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LQD OCA].
-Description: The crystal structures of the Brucella protein TcpB and the TLR adaptor protein TIRAP show structural differences in microbial TIR mimicry
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Jiang, J.]]
+[[Category: Smith, P.]]
+[[Category: Snyder, G A.]]
+[[Category: Xiao, T S.]]
+[[Category: Flavodoxin fold]]
+[[Category: Immune system]]
+[[Category: Myd88]]
+[[Category: Toll-like receptor signaling adaptor]]