4m18: Difference between revisions
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{{STRUCTURE_4m18| PDB=4m18 | SCENE= }} | |||
===Crystal Structure of Surfactant Protein-D D325A/R343V mutant in complex with trimannose (Man-a1,2Man-a1,2Man)=== | |||
{{ABSTRACT_PUBMED_24224757}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/SFTPD_HUMAN SFTPD_HUMAN]] Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. | |||
==About this Structure== | |||
[[4m18]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M18 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024224757</ref><references group="xtra"/><references/> | |||
[[Category: Allen, K.]] | |||
[[Category: Cafarella, T R.]] | |||
[[Category: Calin, O.]] | |||
[[Category: Crouch, E C.]] | |||
[[Category: Goh, B C.]] | |||
[[Category: Hartshorn, K L.]] | |||
[[Category: Rynkiewicz, M J.]] | |||
[[Category: Schulten, K.]] | |||
[[Category: Seaton, B A.]] | |||
[[Category: Seeberger, P H.]] | |||
[[Category: White, M R.]] | |||
[[Category: Carbohydrate recognition domain]] | |||
[[Category: Lectin]] | |||
[[Category: Sugar binding protein]] | |||
[[Category: Surfactant protein]] | |||
Revision as of 10:17, 4 December 2013
Crystal Structure of Surfactant Protein-D D325A/R343V mutant in complex with trimannose (Man-a1,2Man-a1,2Man)Crystal Structure of Surfactant Protein-D D325A/R343V mutant in complex with trimannose (Man-a1,2Man-a1,2Man)
Template:ABSTRACT PUBMED 24224757
FunctionFunction
[SFTPD_HUMAN] Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
About this StructureAbout this Structure
4m18 is a 12 chain structure. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Goh BC, Rynkiewicz MJ, Cafarella TR, White MR, Hartshorn KL, Allen K, Crouch EC, Calin O, Seeberger PH, Schulten K, Seaton BA. Molecular mechanisms of inhibition of influenza by surfactant protein d revealed by large-scale molecular dynamics simulation. Biochemistry. 2013 Nov 26;52(47):8527-38. doi: 10.1021/bi4010683. Epub 2013 Nov, 13. PMID:24224757 doi:http://dx.doi.org/10.1021/bi4010683