3f0u: Difference between revisions
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{{STRUCTURE_3f0u| PDB=3f0u | SCENE= }} | {{STRUCTURE_3f0u| PDB=3f0u | SCENE= }} | ||
===Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and 2,4-Diamino-5-[3-(3-methoxy-5-phenylphenyl)but-1-ynyl]-6-methylpyrimidine=== | ===Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and 2,4-Diamino-5-[3-(3-methoxy-5-phenylphenyl)but-1-ynyl]-6-methylpyrimidine=== | ||
{{ABSTRACT_PUBMED_19249312}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/Q2YY41_STAAB Q2YY41_STAAB]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194] | |||
==About this Structure== | ==About this Structure== | ||
[[3f0u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[3f0u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staab Staab]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F0U OCA]. | ||
==See Also== | ==See Also== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:019249312</ref><references group="xtra"/> | <ref group="xtra">PMID:019249312</ref><references group="xtra"/><references/> | ||
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
[[Category: | [[Category: Staab]] | ||
[[Category: Anderson, A C.]] | [[Category: Anderson, A C.]] | ||
[[Category: Frey, K M.]] | [[Category: Frey, K M.]] | ||