2anq: Difference between revisions
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{{STRUCTURE_2anq| PDB=2anq | SCENE= }} | {{STRUCTURE_2anq| PDB=2anq | SCENE= }} | ||
===Crystal Structure of E.coli DHFR in complex with NADPH and the inhibitor compound 10a.=== | ===Crystal Structure of E.coli DHFR in complex with NADPH and the inhibitor compound 10a.=== | ||
{{ABSTRACT_PUBMED_17125251}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | |||
==About this Structure== | ==About this Structure== | ||
[[2anq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[2anq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ANQ OCA]. | ||
==See Also== | ==See Also== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:017125251</ref><references group="xtra"/> | <ref group="xtra">PMID:017125251</ref><references group="xtra"/><references/> | ||
[[Category: Bacillus coli migula 1895]] | |||
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
[[Category: Brown, E D.]] | [[Category: Brown, E D.]] | ||
[[Category: Daigle, D M.]] | [[Category: Daigle, D M.]] | ||