Single stranded binding protein: Difference between revisions

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<StructureSection load='1eyg' size='500' side='right' frame='true' caption='Structure of Single Stranded DNA-Binding Protein bound to ssDNA (PDB entry [[1eyg]])' scene=''>
<StructureSection load='1eyg' size='500' side='right' frame='true' caption='Structure of Single Stranded DNA-Binding Protein bound to ssDNA (PDB entry [[1eyg]])' scene=''>


===Introduction===
==Introduction==


The single stranded DNA binding protein (SSB) of E. coli plays an important role in three aspects of DNA metabolism – namely in replication, repair and recombination.  During DNA replication, SSB molecules bind to the newly separated DNA strands, keeping the strands separated by holding them in place so that each strand can serve as a template.
The single stranded DNA binding protein (SSB) of E. coli plays an important role in three aspects of DNA metabolism – namely in replication, repair and recombination.  During DNA replication, SSB molecules bind to the newly separated DNA strands, keeping the strands separated by holding them in place so that each strand can serve as a template.


===Structure===
==Structure==


The structure of SSB consists of a homotetramer that has a DNA binding domain that binds to a single strand of DNA.  
The structure of SSB consists of a homotetramer that has a DNA binding domain that binds to a single strand of DNA.  
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</StructureSection>
</StructureSection>


===See Also===
==See Also==





Revision as of 19:58, 30 October 2013

Sandbox Single Stranded DNA-Binding Protein (SSB)Sandbox Single Stranded DNA-Binding Protein (SSB)


Introduction

The single stranded DNA binding protein (SSB) of E. coli plays an important role in three aspects of DNA metabolism – namely in replication, repair and recombination. During DNA replication, SSB molecules bind to the newly separated DNA strands, keeping the strands separated by holding them in place so that each strand can serve as a template.

Structure

The structure of SSB consists of a homotetramer that has a DNA binding domain that binds to a single strand of DNA.


Structure of Single Stranded DNA-Binding Protein bound to ssDNA (PDB entry 1eyg)

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Binding Interactions in the Active SiteBinding Interactions in the Active Site


Structure of Single Stranded DNA-Binding Protein bound to ssDNA (PDB entry 1kaw)

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See AlsoSee Also

ReferencesReferences


PMID: 2087220

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Refayat Ahsen, Rachel Craig, Alexander Berchansky, Michal Harel