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{{STRUCTURE_4bs0| PDB=4bs0 | SCENE= }} | {{STRUCTURE_4bs0| PDB=4bs0 | SCENE= }} | ||
===Crystal Structure of Kemp Eliminase HG3.17 E47N,N300D Complexed with Transition State Analog 6-Nitrobenzotriazole=== | ===Crystal Structure of Kemp Eliminase HG3.17 E47N,N300D Complexed with Transition State Analog 6-Nitrobenzotriazole=== | ||
{{ABSTRACT_PUBMED_24132235}} | |||
==About this Structure== | ==About this Structure== | ||
[[4bs0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoascus_aurantiacus Thermoascus aurantiacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BS0 OCA]. | [[4bs0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoascus_aurantiacus Thermoascus aurantiacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BS0 OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:024132235</ref><references group="xtra"/><references/> | |||
[[Category: Thermoascus aurantiacus]] | [[Category: Thermoascus aurantiacus]] | ||
[[Category: Blomberg, R.]] | [[Category: Blomberg, R.]] |
Revision as of 11:23, 30 October 2013
Crystal Structure of Kemp Eliminase HG3.17 E47N,N300D Complexed with Transition State Analog 6-NitrobenzotriazoleCrystal Structure of Kemp Eliminase HG3.17 E47N,N300D Complexed with Transition State Analog 6-Nitrobenzotriazole
Template:ABSTRACT PUBMED 24132235
About this StructureAbout this Structure
4bs0 is a 2 chain structure with sequence from Thermoascus aurantiacus. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Blomberg R, Kries H, Pinkas DM, Mittl PR, Grutter MG, Privett HK, Mayo SL, Hilvert D. Precision is essential for efficient catalysis in an evolved Kemp eliminase. Nature. 2013 Oct 16. doi: 10.1038/nature12623. PMID:24132235 doi:http://dx.doi.org/10.1038/nature12623
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Thermoascus aurantiacus
- Blomberg, R.
- Gruetter, M G.
- Hilvert, D.
- Kries, H.
- Mayo, S.
- Mittl, P R.E.
- Pinkas, D M.
- Privett, H K.
- Bottom-up enzyme construction
- Computational protein design
- Directed evolution
- Elementary chemical step catalysis
- Kemp elimination
- Lyase-lyase inhibitor complex
- Proton transfer
- Transition state tuning