2p33: Difference between revisions
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==Overview== | ==Overview== | ||
The development of a series of novel aminopyrimidines as inhibitors of | The development of a series of novel aminopyrimidines as inhibitors of c-Jun N-terminal kinases is described. The synthesis, in vitro inhibitory values for JNK1, JNK2 and CDK2, and the in vitro inhibitory value for a c-Jun cellular assay are discussed. | ||
==Disease== | |||
Known diseases associated with this structure: Epileptic encephalopathy, Lennox-Gastaut type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602897 602897]] | |||
==About this Structure== | ==About this Structure== | ||
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[[Category: Mitogen-activated protein kinase]] | [[Category: Mitogen-activated protein kinase]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Ceska, T | [[Category: Ceska, T A.]] | ||
[[Category: Dickson, K | [[Category: Dickson, K M.]] | ||
[[Category: Fortunato, M.]] | [[Category: Fortunato, M.]] | ||
[[Category: Platt, A.]] | [[Category: Platt, A.]] | ||
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[[Category: jnk3 kinase]] | [[Category: jnk3 kinase]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:25:27 2008'' | ||