4j5m: Difference between revisions

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-'''Unreleased structure'''
+{{STRUCTURE_4j5m|  PDB=4j5m  |  SCENE=  }}
+===Structure of the Cargo Binding Domain from Human Myosin Vb===
-The entry 4j5m is ON HOLD
+==Disease==
+[[http://www.uniprot.org/uniprot/MYO5B_HUMAN MYO5B_HUMAN]] Microvillous inclusion disease. The disease is caused by mutations affecting the gene represented in this entry.
-Authors: Nascimento, A.F.Z., Trindade, D.M., Mahajan, P., Berridge, G., Krojer, T., Vollmar, M., Tonoli, C.C.C., Assis, L.H.P., Burgess-Brown, N., von Delft, F., Murakami, M.T.
+==Function==
+[[http://www.uniprot.org/uniprot/MYO5B_HUMAN MYO5B_HUMAN]] May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis (By similarity).<ref>PMID:17462998</ref> <ref>PMID:19542231</ref> <ref>PMID:21282656</ref>
-Description: Structure of the Cargo Binding Domain from Human Myosin Vb
+==About this Structure==
+[[4j5m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J5M OCA].
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Homo sapiens]]
+[[Category: Assis, L H.P.]]
+[[Category: Berridge, G.]]
+[[Category: Burgess-Brown, N.]]
+[[Category: Delft, F von.]]
+[[Category: Krojer, T.]]
+[[Category: Mahajan, P.]]
+[[Category: Murakami, M T.]]
+[[Category: Nascimento, A F.Z.]]
+[[Category: Tonoli, C C.C.]]
+[[Category: Trindade, D M.]]
+[[Category: Vollmar, M.]]
+[[Category: Human myosin vb]]
+[[Category: Intracellular traffic]]
+[[Category: Organelle]]
+[[Category: Protein transport]]
+[[Category: Vesicle]]